Area Engineer, Biologics Building - Lilly Medicine Foundry

At Lilly, we unite caring with discovery to make life better for people around the world. We are a global healthcare leader headquartered in Indianapolis, Indiana. Our employees around the world work to discover and bring life‑changing medicines to those who need them, improve the understanding and management of disease, and give back to our communities through philanthropy and volunteerism. We give our best effort to our work, and we put people first.

We’re looking for people who are determined to make life better for people around the world.

Lilly recently announced a $4.5 billion investment to create the Lilly Medicine Foundry, a new center for advanced manufacturing and drug development. The first‑ever facility of its kind combines research and manufacturing in a single location, enabling us to further develop innovative solutions to optimize manufacturing processes, increase capacity for clinical‑trial medicines, and reduce costs and environmental impact.

The Area Engineer is the site Subject Matter Expert (SME) for the Biologics Building (BB) and the associated ancillary systems within the FUME (Facilities, Utilities Maintenance & Engineering) organization. During the project phase the Area Engineer is a key player in the cross‑functional project team, assisting in the design, construction, commissioning, qualification, start‑up and operational readiness of all systems within the Lilly Medicine Foundry’s BB.

During day‑to‑day operation the Area Engineer is responsible for effectively, reliably and cost‑consciously overseeing and maintaining the site’s BB and associated ancillary systems. This includes maintaining all systems in a state of compliance, in‑control and fit for use to meet the needs of internal customers and/or the business. The Area Engineer will also drive continuous improvement initiatives, manage annual operating expenses and local capital investments, and act as the single point of contact for all residents/customers associated with the BB.

Core responsibilities include:

• Be the SME with deep technical expertise in all systems under responsibility, understanding their applications in pharmaceutical manufacturing, flow charts and process parameters, and awareness of industry trends. This includes, but is not limited to, the following building/equipment systems:
  • Process Rooms:
    • ISO 7/8 Flexible Spaces
    • Single‑Use Bioreactors (SUBs) (50 L‑2000 L)
    • Single‑Use Mixers (SUMs)
    • Chromatography Columns
    • Organic Solvents
    • Biology Safety Cabinets (BSCs)
    • Gas/Temperature Control Units (TCUs)
  • Material Dispensing:
    • Cold rooms/freezers
    • BSC’s and fume hoods
    • Drum handling
  • Media Prep:
    • Agitated vessels
    • Portable SUMs
    • TCUs
  • Buffer Prep: (none listed)
  • Cell Bank:
    • Cryovial Storage System
  • Process Utility Areas
  • Clean in Place (CIP)
  • Caustic Dilution System
  • Water for Injection (WFI)
  • Waste Systems
  • Compressed Gas Systems:
    • Oil‑Free Compressed Air
    • Nitrogen (N₂) – Bulk Liquid
    • Oxygen (O₂) – Bulk Liquid
    • Carbon Dioxide (CO₂) – Bulk Liquid
• Ensure assigned processes align with industry and Lilly standards.
• Support risk‑assessment exercises using tools such as FMEA.
• Participate in teams, committees, or individual projects to achieve FUME’s departmental, site and company goals.

• Lead or participate in projects/changes for all systems in the BB, including design, verification activities (IV/OV/PQ), serving as user representative for capital projects or delivery agent for local projects.
• Develop and maintain documentation such as User Requirement Specifications (URS), test cases, etc., to demonstrate proper installation, qualification and operational control.
• Contribute to process resource assessment, capital plans and expense budgets, prioritizing as appropriate.

• Monitor all BB systems and maintain KPIs to ensure proper operation and compliance with internal/external requirements.
• Act as the single point of contact for the BB to resolve deviations, change controls and CAPAs in collaboration with Operations, Process Engineering, Supply Chain, HSE and Quality Assurance.
• Collaborate within the FUME organization to implement…