Sr. Principal Engineer - Automation Engineering – Hardware, Instrumentation and Controls - Lilly

At Lilly, we unite caring with discovery to make life better for people around the world. We are a global healthcare leader headquartered in Indianapolis, Indiana. Our employees around the world work to discover and bring life‑changing medicines to those who need them, improve the understanding and management of disease, and give back to our communities through philanthropy and volunteerism. We give our best effort to our work, and we put people first.

We’re looking for people who are determined to make life better for people around the world.

Lilly recently announced a $4.5 billion investment to create the Lilly Medicine Foundry, a new center for advanced manufacturing and drug development. The first‑ever facility of its kind, combining research and manufacturing in a single location, the Medicine Foundry will allow Lilly to further develop innovative solutions to optimize manufacturing processes and increase capacity for clinical‑trial medicines, while also reducing costs and environmental impact.

In the project delivery phase and startup phase (startup expected 2026 to 2028), automation engineering roles will be fluid and dynamic as we endeavor to support the project delivery, build a new organization, develop and implement the necessary systems and business processes required to support GMP operations, and build the site culture. This will require significant collaboration, creativity and resilience as the site grows to a full‑scale GMP manufacturing through start‑up.

The Sr. Principal Engineer – Automation Engineering will work as a member of the Automation Engineering Department at Eli Lilly, Foundry. The principal engineer will provide automation support for one or more operating areas across site and/or for capital projects, with primary focus on Instrumentation and Control Hardware. Process Automation is core to delivering a right‑first‑time facility start‑up and continued support of ongoing manufacturing operations into the future.

The Sr. Principal Engineer is also responsible for the productivity and mentorship of the other Engineers in the team with the purpose of ensuring that reliable and compliant control applications and systems are used in the manufacturing itionally, as a key technical expert, the engineer will collaborate with partners within the process control organization and across functional disciplines to support the process control technical agenda, business‑plan priorities, and compliance objectives.

• Site operation support and capital project execution, commissioning & qualification.
• Demonstrated ability in translating technical concepts for executive audience and/or non‑technical stakeholders.
• Deep expertise in Instrumentation design, installation, calibration and troubleshooting.
• Deep expertise in configuration and troubleshooting of Variable Frequency Drives (VFDs).
• Thorough understanding of P&’s, electrical and instrument loop drawings.
• Expertise working with control panels, Delta
  
  V Charms remote I/O panels and Rockwell I/O’s.
• Expertise in performing automation engineering activities including design, tuning and troubleshooting of control loops.
• Define strategies for periodic and corrective maintenance of instruments and control hardware.
• Thorough understanding of various process control communication protocols.
• Develop and implement the Automation Engineering Project Plan.

• System‑level thinking and expertise working with multi‑disciplinary teams.
• Demonstrated ability in resolving complex technical challenges with instrument and control system hardware.
• Technically lead and oversee the work of Site Area leads and System Integrators.
• Develop and review functional requirements, design specifications and test specifications.
• Demonstrated experience with developing and utilizing master maintenance plans.
• Thorough understanding of 21
  
  CFR Part 11, GMP processes.
• Technical leadership in leading projects from concept through commissioning and qualification.
• Demonstrated experience and familiarity with safety‑instrumented systems.
• Lead/participate in design reviews and site system hardware reviews, attend equipment and FATs.
• Provide periodic…