Principal Process Engineer, Lilly Medicine Foundry

Join Lilly:
Small Molecule Process Engineer Opportunity

At Lilly, the work is demanding because patients are waiting. We unite caring with discovery to help make life better for people around the world, knowing that every decision, every detail, and every day matters. Headquartered in Indianapolis, Indiana, our over 50,000 employees around the globe take on complex challenges to discover and deliver life-changing medicines, strengthen how health is understood and managed, and support the communities we serve.

This is hard, urgent, selfless work—but it's work worth doing. If you're driven by purpose and ready to bring your best to work that truly matters for patients, we invite you to join us.

Lilly recently announced a $4.5 billion investment to create the Lilly Medicine Foundry, a new center for advanced manufacturing and drug development. The first-ever facility of its kind, combining research and manufacturing in a single location, the Medicine Foundry will allow Lilly to further develop innovative solutions to optimize manufacturing processes and increase capacity for clinical trial medicines, while also reducing costs and environmental impact.

Lilly is currently constructing an advanced research facility for production of API molecules for clinical trials located in Lebanon, IN. This facility is Lilly's largest investment in a clinical trial manufacturing capacity and is intended to provide APIs for current and future products, including new modalities. This is a unique opportunity to be a part of the startup team for a greenfield manufacturing site, and the successful candidate will help to build the processes and facility to enable a successful startup into GMP manufacturing operations.

We are seeking a small molecule Process Engineer to support the pilot plant facility in Lebanon with a focus on active pharmaceutical ingredient synthesis. This position involves solving technical challenges with equipment design, developing and sustaining process knowledge, optimizing processes, and managing equipment capabilities.

Responsibilities

• Perform impact and risk assessments for unit operations
• Learn the lab and plant design for the reactors including automation recipes and procedures.
• Ensure that people and their environment are safe and that company policies concerning safety are followed.
• Ensure processing equipment remains compliant with internal Quality System requirements, applicable engineering standards, and cGMP requirements.
• Assesses rig fit by receiving the technical data package for new processes and performing modeling, simulations and/or experimental work as required to ensure heat and mass transfer are acceptable when scaling to the plant.
• Active engagement and communication with: HSE, Quality Assurance, Tech Services, Development, Operations, FUME/C&Q, Automation, Maintenance, Environmental Monitoring, and Manufacturing.
• Author, review, or approve high-quality technical reports and regulatory submissions dealing with the work performed by the department. Ensure that records and technical notebooks are adequately maintained.
• Demonstrate engagement and employ a quality mindset in all endeavors by proactively identifying quality issues and communicating appropriately.
• Develop or review plans and timetables for project work.

Basic Requirements

• BS or MS in Chemical Engineering or related discipline
• Minimum of 4 years of experience within a pharmaceutical, biotech, chemical manufacturing, or CMO environment or other relevant batch manufacturing process.
• Qualified applicants must be authorized to work in the United States on a full-time basis. Lilly will not provide support for or sponsor work authorization or visas for this role, including but not limited to F-1 CPT, F-1 OPT, F-1 STEM OPT, J-1, H-1B, TN, O-1, E-3, H-1B1, or L-1

Additional Preferences:

• Supported manufacturing and/or development activities for active pharmaceutical ingredients, intermediates, or other chemicals
• Deep technical interest and understanding in the field of Chemical Engineering
• Familiarity with unit operations including but not limited to chemical reactions, distillation, phase separation, filtration, drying
• Ability to work well in a team environment incorporating a variety of functional relationships and desire to be point of accountability
• Experience with any of the following software packages:
  DeltaV, Dynochem, Aspen, and/or electronic lab notebooks
• Strong analytical and problem-solving skills
• Strong oral and written communication skills for a diverse audience, e.g., both operations staff and management.
• Ability to work on own initiative and as part of a Process Team consisting of a diverse group of management, production, science and engineering professionals
• Understanding of process control systems
• Creativity to identify improvement opportunities and the tenacity/initiative to see them implemented
• Guidance/mentoring of others through processes
• Flexibility to meet business needs

Other Information:

• Initial location at Lilly Technology Center,…