Senior Analytical Scientist- Analytical Sciences and Technology Lilly Medicine Foundry

At Lilly, the work is demanding because patients are waiting. We unite caring with discovery to help make life better for people around the world, knowing that every decision, every detail, and every day matters. Headquartered in Indianapolis, Indiana, our over 50,000 employees around the globe take on complex challenges to discover and deliver life‑changing medicines, strengthen how health is understood and managed, and support the communities we serve.

This is hard, urgent, selfless work—and it’s work worth doing. If you’re driven by purpose and ready to bring your best to work that truly matters for patients, we invite you to join us.

Lilly recently announced a $4.5 billion investment to create the Lilly Medicine Foundry, a new center for advanced manufacturing and drug development. The first‑ever facility of its kind, combining research and manufacturing in a single location, the Medicine Foundry will allow Lilly to further develop innovative solutions to optimize manufacturing processes and increase capacity for clinical trial medicines, while also reducing costs and environmental impact.

The Senior Analytical Scientist role, a technical‑track and lab‑based position, seeks a collaborative, inclusive, and energetic scientist at the Lilly Medicine Foundry to support the production of synthetic and biologic drug substance processes. This role will collaborate with the parent Chemistry Manufacturing and Control (CMC) development organizations to understand the needs of the portfolio and analytical methods required to deliver on the control strategy of the drug substance.

This position will work closely with process engineers, synthetic chemists, process analytical scientists, and production staff, and as such will require good communication and prioritization skills.

• Drive implementation of technical solutions and analytical strategies to enable drug substance production at the Lilly Medicine Foundry leveraging traditional off‑line testing in the laboratories or in‑line/on‑line testing via process analytical technology (PAT) on the production floor.
• Transfer analytical methods from Product Research and Development laboratories with an emphasis on communication with other analytical scientists while making improvements on test methods to improve robustness, accuracy, precision and other attributes outlined by ICH guidelines.
• Demonstrate high learning agility and the ability to understand and exploit effective scientific concepts and methods across multiple subject areas (chemistry, engineering, analytical sciences, data sciences, etc.).
• Plan and manage short‑term and long‑term development activities. Develop and/or review technical agendas and timelines for project work. Recommend resource allocation to accomplish projects according to plans, communicate progress and propose changes in timeline, objectives, or direction.
• Collaborate closely with organizations across development and manufacturing to deliver material and information for clinical trials and regulatory submissions for multiple modalities (small molecules, oligonucleotides, peptides, antibodies, antibody conjugates, and other modalities).
• Serve as a subject matter expert (SME) and technical mentor for team members; provide guidance on experimental design, data interpretation, and problem‑solving.
• Welcome varied perspectives to create new solutions.
• Coordinate instrumentation between different projects to allow equal usage of available tools for project‑specific needs.
• Author or contribute to technical documents including SOPs, technology transfer documents, process flow diagrams, regulatory submissions, patents, and scientific papers.
• Present technical findings and project updates clearly and effectively to the ASAT group and other cross‑functional teams.
• Ensure work and team activities are aligned with all relevant development quality, regulatory, HSE, GLP and GMP requirements.

• B.S. in Chemistry, Analytical Chemistry, Biophysics, Biochemistry, or a closely related STEM field, with at least 8 years of experience in analytical characterization using chromatographic systems…