Senior Analytical Scientist- Analytical Sciences and Technology Lilly Medicine Foundry

Organization And Position Overview

At Lilly, the work is demanding because patients are waiting. We unite caring with discovery to help make life better for people around the world, knowing that every decision, every detail, and every day matters. Headquartered in Indianapolis, Indiana, our over 50,000 employees around the globe take on complex challenges to discover and deliver life‑changing medicines, strengthen how health is understood and managed, and support the communities we serve.

Lilly recently announced a $4.5 billion investment to create the Lilly Medicine Foundry, a new center for advanced manufacturing and drug development. The first‑ever facility of its kind combines research and manufacturing in a single location, allowing Lilly to further develop innovative solutions to optimize manufacturing processes and increase capacity for clinical‑trial medicines, while also reducing costs and environmental impact.

In the Project Delivery Phase and Startup Phase of the project (2026 to 2028), roles will be fluid and dynamic as we endeavor to support the project delivery, build a new organization, develop and implement the necessary systems and business processes required to support GMP operations. This will require significant collaboration, creativity, and resilience as the Lilly Medicine Foundry goes from design, start‑up, and steady‑state operations.

The Senior Analytical Scientist is a technical‑track and lab‑based position that seeks a collaborative, inclusive, and energetic scientist to support the production of synthetic and biologic drug substance processes. This role collaborates with the parent Chemistry Manufacturing and Control (CMC) development organizations to understand portfolio needs and analytical methods required to deliver on the control strategy of the drug substance. The position works closely with process engineers, synthetic chemists, process analytical scientists, and production staff, requiring strong communication and prioritization skills.

The ASAT group consists of high‑level scientists focused on implementing new technologies and analytical process improvements. This position works cross‑functionally within the site and across the network to identify, develop, and employ new technological solutions to deliver the required information to the project teams. The role is key to ensuring a strong safety culture and establishing a safety, quality, and continuous‑improvement mindset within the organization.

• Drive implementation of technical solutions and analytical strategies to enable drug substance production at the Lilly Medicine Foundry, leveraging traditional off‑line testing in the laboratories or in‑line/on‑line testing via process analytical technology (PAT) on the production floor.
• Transfer analytical methods from Product Research and Development laboratories with an emphasis on communication while making improvements on test methods to enhance robustness, accuracy, precision and other attributes outlined by ICH guidelines.
• Demonstrate high learning agility and the ability to understand and exploit effective scientific concepts and methods across multiple subject areas (chemistry, engineering, analytical sciences, data sciences, etc.).
• Plan and manage short‑term and long‑term development activities. Develop and/or review technical agendas and timelines for project work. Recommend resource allocation to accomplish projects according to plans, communicate progress and propose changes in timeline, objectives, or direction.
• Collaborate closely with organizations across development and manufacturing to deliver material and information for clinical trials and regulatory submissions across multiple modalities (small molecules, oligonucleotides, peptides, antibodies, antibody conjugates, and other modalities).
• Serve as a subject‑matter expert (SME) and technical mentor for team members; provide guidance on experimental design, data interpretation, and problem‑solving.
• Welcome varied perspectives to create new solutions.
• Coordinate instrumentation between different projects to allow equal usage of available tools for project‑specific needs.
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