Senior Research Associate , Bioanalytical

Job Summary

At Keros, our mission is to deliver significant clinical benefit to a wide range of patients with disorders that are linked to dysfunctional signaling of the transforming growth factor-beta (TGF-ß) family of proteins. With a focus on developing differentiated product candidates that are designed to alter TGF-β signaling, we aim to target the pathways critical for the growth, repair and maintenance of blood cells and a number of tissues, including bone, skeletal muscle, adipose and heart tissue.

We believe our product candidates have the potential to unlock the full therapeutic benefits of modulating the TGF-β superfamily and provide disease-modifying benefit to patients.

Keros is seeking a Senior Research Associate with working knowledge of large molecule/biologics bioanalytical techniques and laboratory skills. This person will develop and perform bioanalytical methods for programs in preclinical and clinical development, document the methods used, interpret, and summarize the data collected. This role will report into the Bioanalytical Scientist and will be responsible for activities related to the development, qualification and bio-analysis for non-regulated methods and samples in support of drug candidate development.

This individual will have the opportunity to directly contribute to the bioanalytical assay development for platform and therapeutic areas, and work in a fast-paced environment as part of a highly collaborative team.

This is a full-time laboratory position based in Lexington, MA.

• Design, develop, optimize, and execute bioanalytical assays to support nonclinical studies, including PK, PD, biomarker, and ADA/immunogenicity endpoints
• Execute ligand‑binding assays and cell‑based assays, ensuring robust assay performance, data quality, and compliance with applicable guidelines
• Help to identify and develop novel bioanalytical approaches to address important scientific questions in support of the discovery and development of novel drug candidates
• Collaborate, as needed, with external vendors for the transfer of primarily ELISA/ECL based PK, ADA, and biomarker assays to support development of large molecule drug candidates
• Perform internal testing of preclinical samples
• Other duties and responsibilities as required by study needs

• Bachelor’s or master’s degree in cell biology, molecule biology, biochemistry, immunology, biotechnology or related field with at least 4 to 6 years of relevant experience in an industrial pharmaceutical/biotechnology lab setting
• Hands‑on experience with PK and ADA/immunoassay development and statistical data analysis is required
• Familiarity with FDA guidelines for bioanalytical methods
• Experience with biomarker methods (ELISA, MSD, Luminex) is a plus
• Excellent attention to detail, critical thinking, and data interpretation
• Ability to work with demanding deadlines and in a fast‑paced work environment
• Excellent written and verbal communication and documentation skills
• Willingness to learn, excellent teamwork and collaborative skills

Potential base pay range $74,000—$99,000 USD

Keros Therapeutics is an Equal Opportunity employer. All qualified applicants will receive consideration for employment without regard to race, color, religion, sex including sexual orientation and gender identity, national origin, disability, protected veteran status, or any other characteristic protected by applicable federal, state, or local law.