Research Associate II, Analytical Development

At Keros, our mission is to deliver significant clinical benefit to a wide range of patients with disorders that are linked to dysfunctional signaling of the transforming growth factor-beta (TGF-ß) family of proteins. With a focus on developing differentiated product candidates that are designed to alter TGF-β signaling, we aim to target the pathways critical for the growth, repair and maintenance of blood cells and a number of tissues, including bone, skeletal muscle, adipose and heart tissue.

We believe our product candidates have the potential to unlock the full therapeutic benefits of modulating the TGF-β superfamily and provide disease-modifying benefit to patients.

As a Research Associate II, Analytical Development, you will participate in activities to support the development and testing of analytical methods in support of process development, release, stability and characterization assays for Fc-fusion molecules.

• Assist in the development of chromatography and electrophoresis based analytical methods to be used for product release, stability, and characterization testing
• Prioritize and perform timely testing that enables process and MSAT teams to meet project timelines. This will require occasional weekend work initially.
• Critically evaluate analytical data to support method development decisions and product quality comparisons
• Maintain accurate and timely experiment records in electronic laboratory notebook (ELN)
• Summarize and present data in a clear and meaningful way
• Author and review analytical test methods and development reports
• Participate in team meetings with external testing labs
• Participate in laboratory organization activities such as ordering and receipt of reagents and samples

• B.S. or M.S. in Analytical Chemistry, Biochemistry, Chemical Engineering, Pharmaceutical Sciences or related scientific discipline with a minimum of 1-3 years of CMC analytical development experience in biotech/pharma
• Hands‑on experience with various analytical methods for measuring the purity of biologics and residual process impurities (i.e. chromatography, capillary electrophoresis, ELISA, etc.)
• Experience with chromatography and capillary electrophoresis data analysis software
• Excellent laboratory, critical thinking, scientific problem‑solving, and organizational skills
• Familiarity with good documentation requirements and industry guidance
• Knowledge of statistical approaches for data interpretation and analytical method development
• Motivated, detail‑oriented, naturally curious individual with a creative approach to scientific problem solving
• Excellent spoken and written communication skills

This pay range represents the base hourly rate or base annual full-time salary for all positions in the job grade within which this position falls. The actual base salary offer will depend on a variety of factors including experience, education, and other relevant factors.

Potential base pay range: $51 — $60 USD

Keros Therapeutics is an Equal Opportunity employer. All qualified applicants will receive consideration for employment without regard to race, color, religion, sex including sexual orientation and gender identity, national origin, disability, protected veteran status, or any other characteristic protected by applicable federal, state, or local law.