Scientist II, Bioanalytical

About the Department

Our Research & Development organization brings together the best minds in life science innovation. The teams located in facilities in Lexington and Waltham reflect the full R&D continuum, from early research through late-stage clinical development. We are building a distinct R&D community based on collaboration, partnerships, and cutting‑edge research across multiple modalities and therapeutic areas. We recognize that improving human health starts here and that patients rely on us.

As an LCMS Bioanalytical Scientist II, you will design, develop, and execute novel quantitative liquid chromatographic and mass spectroscopic (LCMS) assays in support of in‑vivo and in‑vitro pharmacology studies. You will work with proteins, peptides, small molecules, oligonucleotides, and their conjugates to advance PK/PD and biomarker discovery. Your work will include experimental design, data integrity, reproducibility, and clear communication of results to diverse project teams within our U.S. R&D Hub and global organization.

Reports to the head of the Bioanalysis Department. Works collaboratively with project teams, research colleagues in greater Boston R&D Hub, and global partners. Does not manage other employees or contingent workers.

• Contribute subject matter and technical expertise to research projects, applying early drug discovery knowledge to drive outcomes.
• Provide LCMS expertise in qualitative and quantitative analysis, PK assays, metabolite identification, and biomarker exploration.
• Design and perform LCMS analytical methods that are fit for purpose and produce quality, value‑adding data.
• Manage relationships with CROs, including contract establishment, statement of work, and oversight of data.
• Critically evaluate experimental results, applying mathematical modelling and software to produce clear written and oral summaries.
• Independently draw conclusions from experiments and provide input on future directions.
• Communicate experimental results within and outside the functional area, guiding project teams and stakeholders.
• Maintain and troubleshoot laboratory instruments and manage consumables, reagents, and sample inventories.

• Bachelor's degree required. Undergraduate with 8+ years of relevant experience, master’s with 6+ years, or PhD with 2+ years of relevant experience.
• Relevant experience includes:
  • Subject matter expertise in LCMS assay concepts, techniques, and technology platforms.
  • Proficiency in analyte extraction and sample preparation from complex biological matrices.
  • Experience with diverse modalities (antibodies, proteins, peptides, small molecules, oligonucleotides).
  • Solid understanding of PK/PD modelling in preclinical animal models.
  • Practical skills with LCMS systems, methods, and software (e.g., Thermo Scientific, Sciex, Waters, Xcalibur, Chromeleon, Bio Pharma Finder, Proteome Discoverer).
  • Experience working in a bioanalytical laboratory.
• Preferred experience includes:
  • Lab automation and liquid handling instrumentation.
  • Experience using Win Nonlin.
  • Experience working with CROs.
  • Knowledge of GLP bioanalytical principles.
• Excellent verbal and written communication skills.
• Outstanding project management, organizational, and time‑management skills.

Base compensation range: $99,600 to $184,200, with company bonus and potential long‑term incentive compensation. Benefits include medical, dental, vision, life insurance, disability insurance, 401(k), flexible spending accounts, employee assistance program, tuition reimbursement, and voluntary benefits such as group legal and pet insurance. Time off policies include sick leave, flexible vacation, and parental leave.

Nova Nordisk is an equal opportunity employer. Qualified applicants will receive consideration for employment without regard to race, ethnicity, color, religion, sex, gender identity, sexual orientation, national origin, disability, protected veteran status, or any other characteristic protected by local, state, or federal laws, rules or regulations.