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Cell Line Development Scientist

Job in Lexington, Fayette County, Kentucky, 40598, USA
Listing for: Demeetra
Full Time position
Listed on 2026-07-22
Job specializations:
  • Research/Development
    Research Scientist, Biotech Research
Salary/Wage Range or Industry Benchmark: 110000 - 150000 USD Yearly USD 110000.00 150000.00 YEAR
Job Description & How to Apply Below

Demeetra is seeking highly motivated Cell Line Development Scientists to join our fast-paced team advancing next-generation gene editing technologies in bioproduction. This role is designed for someone who is eager, hands-on, detail-driven, and experienced enough to contribute with minimal onboard training. The successful candidate must be driven by a culture of excellence and ready for intense, high-expectation, hands-on CLD workflows
, bringing industry experience that enables them to contribute at a high level from day one, ideally in a CRO or CDMO setting.

About the Role

You will be a key contributor in developing engineered CHO cell lines and optimizing upstream processes that support Demeetra’s cutting-edge gene editing platforms. This position is ideal for recent graduates who preferably have 1-2 years of cell culture experience
, and are eager to take ownership of experimental design, workflow execution, and timeline-driven deliverables.

Responsibilities
  • Execute CHO cell culture processes across shake flasks and Spin Tube formats
  • Perform transfection, selection, clone screening, and single-cell cloning workflows
  • Support upstream development with high attention to process consistency and data integrity
  • Run titer and basic downstream quality assays to assess productivity and cell line performance
  • Collaborate cross-functionally to implement advanced gene editing technologies in CLD
  • Contribute to workflow design, documentation, and continuous process improvement
  • Maintain a culture of excellence, accountability, and meeting or exceeding timelines
Required Qualifications
  • PhD in biology, biochemistry, biotechnology, or related field required
  • 1–2+ years tissue culture experience in cell line development or upstream processing (CDMO or CLD company strongly preferred)
  • Demonstrated proficiency in:
  • CHO cell culture
  • Shake flask and Spin Tube fed-batch processes
  • Single-cell cloning
  • Titer determination and standard downstream quality assessments (HPLC experience is a plus)
  • Ability to thrive in a high-expectation, fast-moving environment
  • Strong communication, organization, and documentation skills
Why Join Demeetra?

This is an opportunity to join a growing company at the forefront of gene editing applied to cell line development and bioprocessing. You will have significant hands-on impact
, work with advanced technologies, and be part of an intensely collaborative and rewarding environment.

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