Lab Manager

Orum Therapeutics is a KOSDAQ-listed biotech pioneering degrader-antibody conjugate (DAC) therapies. Our Lexington lab is the operational core of our US R&D — and this role keeps it running. We're looking for a Lab Manager who walks in every morning asking "how can I help?" — and then goes and does it.

This is a hands‑on, high‑ownership lab operations role supporting both the Chemistry and Biology teams. You'll oversee the day-to-day functioning of a ~9,000 sq ft research lab, manage a part‑time Lab Associate who you'll help hire, and be the connective tissue between scientists, vendors, facilities, and finance. Chemistry instrument fluency is non‑negotiable — HPLC, LC‑MS/MS, and lyophilizers are mission‑critical to our research and need a dedicated owner who can troubleshoot, not just schedule PMs.

• Hire, onboard, and directly supervise a part‑time Lab Associate; scope their role and co‑design their responsibilities
• Mentor the Lab Associate and support their development
• Serve as the escalation point for lab ops issues across both chemistry and biology teams

• Oversee common area cleanliness, organization, and decontamination of high‑touch surfaces
• Coordinate receipt of lab deliveries — open, inventory, and log incoming chemical and reagent shipments before distribution to scientists; maintain chemical inventory in the ELN
• Manage glasswash and autoclave cycles
• Order and stock consumables, PPE, and lab supplies; confirm scope of reagent ordering with science team leads
• Own preventive maintenance scheduling for chemistry and biology instruments: LC‑MS/MS, HPLC/UHPLC, lyophilizers, nitrogen generators, flow cytometers, CO₂ incubators, plate readers, glassware washers, and cold storage
• Troubleshoot equipment issues directly — not just elevate; chemistry instrument knowledge is the priority
• Host service technician visits; manage service contract renewals
• Maintain chemical inventory and emergency backup coverage for ELN entry
• Willingness to learn LC‑MS/MS monthly calibration (~4 hours/month) — not required at onboarding, but expected over time

• Manage all R&D outbound shipments including MSDS/CoA creation, shipping invoices, and international compliance — this is a high‑volume, time‑intensive task requiring dedicated oversight
• Coordinate inbound shipments in partnership with Inventory Control Associate
• Ensure DOT/IATA compliance including hazardous materials documentation and dry ice certification

• Perform weekly safety inspections: safety showers, eyewashes, fire extinguishers
• Coordinate chemistry and biological waste disposal
• Manage DOT/hazmat compliance and dry ice (IATA) certifications for relevant staff
• Oversee EHS compliance and SOP maintenance in partnership with Safety Partners;
  Safety Partners leads training design and delivery — Lab Manager coordinates scheduling, tracking, and DIA‑approved pipeline completion
• Maintain Subtenant fire warden accountability list
• Support pest control program decisions in coordination with Facility Manager

• Generate POs for lab materials and equipment
• Manage lab software license inventory and renewals
• Participate in quarterly budget activities and interface with finance team on lab‑related spend

• Serve as primary point of contact for external contractors: plumbers, electricians, fire department, Building Landlord
• Coordinate facility‑related issues (HVAC/thermostat, mechanical room, glass panel contingency) with building management and facility manager
• Support any lab moves, buildouts, and facility improvements with facility manager; potential to absorb facilities coordination currently shared with Operations

• Own and maintain the Ops ticketing system (Smartsheet)
• Maintain the Confluence US Lab Operations Wiki as the living documentation home for lab procedures and SOPs
• Manage software license renewals for lab team in coordination with IT

• Hire, onboard, and directly supervise a part‑time Lab Associate; scope their role and co‑design their responsibilities
• Mentor the Lab Associate and support their…