Principal Scientist - Global Drug Discovery
Listed on 2026-06-21
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Research/Development
Research Scientist
Principal Scientist - Global Drug Discovery
Facility:
Research
Location:
Lexington, MA, US
About the Department
Our Research & Development organization brings together the best minds in life science innovation. The teams located in facilities in Lexington, Watertown, Cambridge and Plainsboro reflect the full R&D continuum, from early research through late‑stage clinical development. Here, we are building for the future, creating a distinct R&D community based on collaboration, partnerships, and cutting‑edge research across multiple modalities and therapeutic areas.
We recognize that improving human health starts here and that patients rely on us. Our R&D hub merges biotech speed and agility with large pharmaceutical company quality, resources, and stability, uniting the best of both worlds to develop new medicines for patients.
The Position
The Principal Scientist will provide scientific leadership in the identification and validation of new drug targets, advancing novel therapies to the clinic, and developing technologies to accelerate drug research. This will be achieved by functioning as a subject matter expert that provides strategic guidance to project teams, evaluates emerging targets and technologies, and proposes and oversees external collaborations and strategic partnerships.
The Principal Scientist may mentor senior colleagues in the department and will represent the organization to the external scientific community through publication and presentation of highly impactful research.
Relationships
Reports to the head of the relevant department at Novo Nordisk Research Center Seattle. Internal relationships include working closely with technical staff and other members of the scientific leadership team; regular collaborations with members of other research departments at NNRCSI; and frequent interaction with project managers and other colleagues across global R&D. Individual may indirectly supervise less experienced team members. Individual will interact with external research collaborators both academia‑ and industry‑based.
Essential Functions
- Proven subject matter expertise. Demonstrates a specialized depth and/or breadth of expertise, and engages relationships with other key areas related to drug development in the pharmaceutical industry
- Work with full autonomy on extremely complex tasks requiring highly‑specialized knowledge of strategic importance to SVP area
- Provide expert‑level guidance for project team related to experimental strategies to evaluate emerging targets, biologies or technologies
- Effectively communicate and collaborate across global sites and set project strategy by providing leadership of cross‑functional project teams
- Propose and lead external collaborations and strategic partnerships to further company goals related to therapeutic area
- Contribute subject matter expertise to develop the research agenda with a clear understanding of the link between scientific project goals and overall long‑term business needs
- Propose new projects that support the strategic agenda and address gaps in technological capabilities and therapeutic areas
- Represent the organization through external communication of impactful scientific research in the form of presentation at external conferences and publication in scientific journals and patents
- Maintains a deep understanding of theoretical knowledge and a connection to the external scientific community through continuous evaluation of relevant literature
- Leads global, cross‑functional experimental teams to achieve project goals. Provides significant mentorship and training of junior and senior colleagues within field of expertise
Qualifications
- Bachelor’s degree required. Relevant Post‑graduate or industry experience required
- 22+ years’ relevant experience required, Master’s Degree with 16 years relevant industry or post‑doctorate experience can be considered. PhD with 10 years relevant industry or post‑doctorate experience can be considered
- Relevant required experience includes: insert subject matter expertise
- Preferred experience includes: insert subject matter preferred experience
- Demonstrates excellent verbal and written communication skills
The base…
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