Senior Research Associate , Bioanalytical

At Keros, our mission is to deliver significant clinical benefit to a wide range of patients with disorders linked to dysfunctional signaling of the transforming growth factor-beta (TGF-ß) family of proteins. With a focus on developing differentiated product candidates that alter TGF-β signaling, we aim to target the pathways critical for the growth, repair, and maintenance of blood cells and a number of tissues, including bone, skeletal muscle, adipose, and heart tissue.

We believe our product candidates have the potential to unlock the full therapeutic benefits of modulating the TGF-β superfamily and provide disease-modifying benefit to patients.

Keros is seeking a Senior Research Associate with working knowledge of large molecule/biologics bioanalytical techniques and laboratory skills. This person will develop and perform bioanalytical methods for programs in preclinical and clinical development, document the methods used, interpret, and summarize the data collected. This role will report into the Bioanalytical Scientist and will be responsible for activities related to the development, qualification, and bio-analysis for non-regulated methods and samples in support of drug candidate development.

This individual will directly contribute to the bioanalytical assay development for platform and therapeutic areas in a fast-paced, highly collaborative environment. This is a full-time laboratory position based in Lexington, MA.

• Design, develop, optimize, and execute bioanalytical assays to support nonclinical studies, including PK, PD, biomarker, and ADA/immunogenicity endpoints.
• Execute ligand-binding assays and cell-based assays, ensuring robust assay performance, data quality, and compliance with applicable guidelines.
• Help to identify and develop novel bioanalytical approaches to address scientific questions supporting the discovery and development of novel drug candidates.
• Collaborate, as needed, with external vendors for the transfer of primarily ELISA/ECL based PK, ADA, and biomarker assays to support the development of large molecule drug candidates.
• Perform internal testing of preclinical samples.
• Other duties and responsibilities as required by study needs.

• Bachelor’s or master’s degree in cell biology, molecular biology, biochemistry, immunology, biotechnology, or a related field with at least 4 to 6 years of relevant experience in an industrial pharmaceutical or biotechnology lab setting.
• Hands‑on experience with PK and ADA/immunoassay development and statistical data analysis is required.
• Familiarity with FDA guidelines for bioanalytical methods.
• Experience with biomarker methods (ELISA, MSD, Luminex) is a plus.
• Excellent attention to detail, critical thinking, and data interpretation.
• Ability to work with demanding deadlines in a fast‑paced environment.
• Excellent written and verbal communication and documentation skills.
• Willingness to learn, excellent teamwork, and collaborative skills.

$74,000—$99,000 USD

Keros is an inclusive company. We believe that diversity drives innovation. We continue to build an inclusive culture that encourages, supports, and celebrates the diverse voices of our employees. As such, Keros takes a holistic approach in mentoring, coaching, and developing all of our Keros team members.

Keros Therapeutics is an Equal Opportunity employer. All qualified applicants will receive consideration for employment without regard to race, color, religion, sex—including sexual orientation and gender identity—national origin, disability, protected veteran status, or any other characteristic protected by applicable federal, state, or local law.