Senior Scientist , In Vivo Pharmacology

Facility:
Research

Location:

Lexington, MA, US

Our Research & Development organization brings together the best minds in life science innovation. The teams located in facilities in Lexington, Watertown, Cambridge and Plainsboro reflect the full R&D continuum, from early research through late-stage clinical development. Here, we are building for the future, creating a distinct R&D community based on collaboration, partnerships, and cutting‑edge research across multiple modalities and therapeutic areas.

We recognize that improving human health starts here and that patients rely on us. Our R&D hub merges biotech speed and agility with large pharmaceutical company quality, resources, and stability, uniting the best of both worlds to develop new medicines for patients. This position is in the Diabetes Discovery Pharmacology team in the Diabetes Research US research area based in Lexington.

The Senior Scientist I is expected to have a proven track record in diabetes and metabolism research and drug discovery and be a self‑motivated team player with strong communication skills. Experience with small molecules would be advantageous. The Senior Scientist I will be expected to manage and lead multiple activities in parallel within a matrix environment and have a collaborative mind‑set with a strong personal drive and dedication.

This position requires a flexible attitude and the ability to change focus as required by projects and shifting priorities. The Senior Scientist I will be responsible for strategy implementation and operations for conducting and summarizing non‑clinical in vivo studies internally and externally in the support of new drug evaluations to support our Diabetes research pipeline. The senior scientist I is expected to design, coordinate, execute as part of a team and report pre‑clinical pharmacokinetic and pharmacodynamic in vivo experiments within research projects as part of target validation, target maturation, or mode‑of‑action studies.

Develop and improve in vivo models supporting non‑clinical studies, optimize and develop assays necessary for endpoint analyses, take an active role in research projects, and contribute to innovation by identifying and exploring new therapeutic targets and principles. Communicate evaluations and implications of data packages internally, externally, and in regulatory submissions as relevant.

Demonstrates subject matter expertise. Requires in-depth knowledge and experience. Solid knowledge and skills relevant for NN Business cross‑functional understanding. Strong knowledge within a specific process and extensive business understanding across SVP area. Uses best practices and knowledge of internal or external business issues to improve products or services. Works independently; receives minimal guidance. Acts as a resource for colleagues with less experience;

may direct the work of other staff members. Perceived as expert within one or several key processes across the VP/CVP area. Handling specialist tasks of high complexity critical to the CVP area.

Hands‑on work involving highly complex activities; lead project (target, biology, or technology‑related) involving coordination of multiple experimental activities & groups, recommends/is responsible for ensuring realistic project timelines & deliverables, work closely with project manager; deep understanding of subject matter & demonstrates creative, independent thinking to identify & address disease/biology‑related questions/gaps, potentially across therapeutic areas; represent NN at conferences & global meetings;

may propose & lead external collaborations; author internal reports & external publications; recommend, present, & champion new targets or methodologies. May mentor or directly supervise less experienced team members based on business need, skill, and/or interest.

Reports to the head of the relevant department at Novo Nordisk. Internal relationships include working closely with technical staff & other members of the scientific leadership team; regular collaborations with members of other research departments at Novo Nordisk; & frequent interaction…