Research Associate, Oligo Synthesis and Chemistry

Research Associate
- Contract
- Lexington, MA

Join the forefront of biotech innovation – turn breakthrough science into life‑changing therapies.

Proclinical is seeking a motivated Research Associate to join our client's team in the US.

The successful candidate focuses on oligonucleotide synthesis and chemistry, supporting discovery-related activities in a dynamic biotech environment. You will play a key role in fulfilling compound requests, ensuring sample quality, and contributing to cutting‑edge research in immuno‑oncology and pharmaceuticals.

• Strong attention to detail and commitment to data integrity.
• Excellent organizational and time management skills with the ability to multitask.
• Effective communication and problem‑solving abilities.
• Proficiency in common laboratory operations, including pipetting, dilution, and UV measurement.
• Experience with UHPLC and LC-MS operation and analysis is strongly preferred.
• Background in analytical chemistry is highly desirable.
• Educational background:
  Master’s degree with relevant experience or Bachelor’s degree with additional industry experience.

• Fulfill compound requests accurately and ensure quality for in vitro and in vivo assays.
• Analyze oligonucleotides using LC-MS and UHPLC for identification and purity assessment.
• Operate Hamilton Star liquid handler for high‑throughput sample preparation in 96‑well plates.
• Perform quality control assays, including UV, pH, osmolality, and bacterial endotoxin testing.
• Maintain an accurate and traceable inventory of oligonucleotides.
• Communicate effectively with team members and requestors to support multiple projects.
• Document experimental results in an electronic lab notebook (ELN) and register relevant sample data.