Downstream Engineer III

Downstream Process Development, Engineer III Responsibilities

• Execute chromatography, harvest operations, ultrafiltration/diafiltration, and viral clearance experiments (may also support bioconjugation).
• Support downstream biotherapeutics process development across micro, bench, and pilot scales for early- and late-stage programs.
• Maintain laboratory equipment and support instrument readiness.
• Plan and execute larger experiments with more senior process engineers.
• Document experiments in electronic laboratory notebooks; maintain timely, complete records.
• Perform basic data analysis and support study conclusions.
• Prepare technical summaries and written study updates.
• Follow established lab/process development procedures, including quality and safety requirements.
• Identify continuous improvement opportunities in workflows, data capture, and experimental execution.
• Assist with small projects/tasks under close supervision; advise peers/junior team members when needed.

• Bachelor’s degree with 2+ years relevant experience, or Master’s degree with relevant experience, in chemical engineering, chemistry, biochemistry, biotechnology, or related field.
• Experience with chromatography, harvest, ultrafiltration/diafiltration, and viral clearance steps.
• Some relevant experience in process development, protein purification, or related lab setting.
• Experience with basic bioprocess control systems.
• Experience using electronic laboratory notebooks.
• Ability to perform basic data analysis and present results clearly in writing.
• Familiarity with technical writing.
• Understanding of lab practices, process development methods, and quality requirements.
• Ability to follow detailed procedures and maintain accurate records under close supervision.
• Comfort with emerging digital tools and AI-enabled processes for data analysis/documentation/workflow improvement.