Research Associate, Oligo Synthesis and Chemistry

Research Associate
- Contract
- Lexington, MA

Join the forefront of biotech innovation—turn breakthrough science into life‑changing therapies. Proclinical is seeking a motivated Research Associate to join our client’s team in the US.

The successful candidate focuses on oligonucleotide synthesis and chemistry, supporting discovery‑related activities in a dynamic biotech environment. You will play a key role in fulfilling compound requests, ensuring sample quality, and contributing to cutting‑edge research in immuno‑oncology and pharmaceuticals.

• Strong attention to detail and commitment to data integrity.
• Excellent organizational and time‑management skills with the ability to multitask.
• Effective communication and problem‑solving abilities.
• Proficiency in common laboratory operations, including pipetting, dilution, and UV measurement.
• Experience with UHPLC and LC‑MS operation and analysis is strongly preferred.
• Background in analytical chemistry is highly desirable.
• Educational background:
  Master’s degree with relevant experience or Bachelor’s degree with additional industry experience.

• Fulfill compound requests accurately and ensure quality for in vitro and in vivo assays.
• Analyze oligonucleotides using LC‑MS and UHPLC for identification and purity assessment.
• Operate Hamilton Star liquid handler for high‑throughput sample preparation in 96‑well plates.
• Perform quality control assays, including UV, pH, osmolality, and bacterial endotoxin testing.
• Maintain an accurate and traceable inventory of oligonucleotides.
• Communicate effectively with team members and requestors to support multiple projects.
• Document experimental results in an electronic lab notebook (ELN) and register relevant sample data.

For questions or more information, please contact Mike Raletz at

Proclinical is a leading life sciences recruiter focused on finding exceptional people and matching them with the finest positions across the globe. Proclinical is acting as an Employment Agency in relation to this vacancy.