Quantitative Virology-Immunology - Postdoctoral Researcher

Quantitative Virology-Immunology - Postdoctoral Researcher

We have an opening for a postdoctoral researcher in quantitative virology and immunology to contribute to interdisciplinary projects at the intersection of mechanistic virology, host-pathogen interactions, structural modeling, and rational vaccine design.

The successful candidate will help drive experimental biology for projects that connect computational protein interface predictions and partner-generated interaction maps to functional biological outcomes. Current applications include mapping and validating virus-host receptor interfaces, evaluating engineered protein variants, characterizing viral antigen and immune recognition interfaces, and supporting immunogen-design efforts aimed at steering protective immune responses.

This position is ideal for an experimental virologist, immunologist, cell biologist, or protein-interface biologist with strong quantitative instincts and working fluency with protein structures, structural models, and computational design. Candidates are not expected to be primary developers of computational models but should be comfortable using structural and computational results to design rigorous experiments, interpret uncertainty, and make biological decisions. The work supports LLNL missions in biosecurity, threat preparedness, and biodefense.

This position is in the Microbiology/Immunology Group in the Biosciences and Biotechnology Division within the Physical and Life Sciences Directorate.

Applicants are encouraged to submit a complete application package that includes a cover letter outlining their research interests, relevant experience, and alignment with the research program; a curriculum vitae (CV) with a publication list; and contact information for three professional references. Please note that incomplete applications will not be considered.

This is a two-year term appointment with the possibility of extension to a maximum of three years.