Director, Quantitative Pharmacology Lead

Are you a seasoned pharmacometrician who enjoys solving complex development challenges, influencing strategy, and working directly with biotech and pharmaceutical clients?

An established scientific consultancy at the forefront of model-informed drug development is seeking an experienced Pharmacometrician to play a key role in delivering high-impact projects across a diverse portfolio of drug development programmes. This is a highly visible position that combines technical excellence with client engagement, commercial input, and scientific leadership.

In this role, you will lead and deliver pharmacometric analyses that directly inform critical development decisions. Working with multidisciplinary teams and external clients, you will design modelling strategies, develop quantitative frameworks, and translate complex data into actionable recommendations.

You'll have the opportunity to contribute across the full project lifecycle while helping shape new service offerings and supporting the continued growth of the business.

• Create and apply population PK, PK/PD, exposure-response, and clinical trial simulation models
• Analyse preclinical and clinical datasets, from data preparation through to model development, validation, simulation, interpretation, and reporting
• Oversee additional modelling methodologies, including PBPK, QSP, mechanistic modelling, and NCA
• Lead client projects, providing scientific direction and strategic recommendations
• Support proposal development, project scoping, and client solution design
• Build trusted client relationships and identify opportunities for further collaboration
• Represent the organisation within the wider scientific community through conferences, publications, and industry engagement
• Stay at the forefront of developments in pharmacometrics, model-informed drug development, and regulatory science

You are an accomplished modeller with a strong track record of applying pharmacometric approaches to support drug development programmes.

• Approximately 6+ years' experience within pharma, biotech, CRO, or consulting environments
• Strong expertise in population PK, PK/PD, exposure-response modelling, and clinical trial simulation
• Advanced proficiency in NONMEM, R, or similar modelling software
• Experience leading complex modelling projects with direct stakeholder or client interaction
• Involvement in clinical development programmes and regulatory submissions/interactions
• Experience mentoring, supervising, or leading small scientific teams