Synthetic Chemistry Lead

Join to apply for the Synthetic Chemistry Lead, London role at Isomorphic Labs

Isomorphic Labs is applying frontier AI to help unlock deeper scientific insights, faster breakthroughs, and life-changing medicines with an ambition to solve all disease.

The future is coming. A future enabled and enriched by the incredible power of machine learning. A future in which diseases are curtailed or cured starting with better and faster drug discovery.

Come and be part of an interdisciplinary team driving groundbreaking innovation and play a meaningful role in contributing towards us achieving our ambitious goals, while being a part of an inspiring and collaborative culture.

The world we want tomorrow is the one were building today. It starts with the culture at this company. It starts with you.

Isomorphic Labs (Iso Labs) was launched in 2021 to advance human health by building on and beyond the Nobel-winning Alpha Fold system. Since then, our interdisciplinary team of drug discovery experts and machine learning specialists has built powerful new predictive and generative AI models that accelerate scientific discovery at digital speed.

Our name comes from the belief that there is an underlying symmetry between biology and information science. By harnessing AIs powerful capabilities, we can use it to model complex biological phenomena to help design novel molecules, anticipate how drugs will perform and develop innovative medicines to treat and cure some of the worlds most devastating diseases.

We have built a world-leading drug design engine comprising AI models that are capable of working across multiple therapeutic areas and drug modalities. We are continually innovating on model architecture and developing cutting-edge capabilities to advance rational drug design.

Every day, and with each new breakthrough, were getting closer to the promise of digital biology, and achieving our ambitious mission to one day solve all disease with the help of AI.

Our dynamic team of Synthetic Chemists and CRO Leads are dedicated to transforming drug design and manufacturing. We work in partnership with our AI/ML and drug discovery colleagues to support all phases of chemistry, from early to late stages, as well as managing our extensive external CRO team. We promote a supportive atmosphere where the diverse expertise of every team member is recognised and appreciated.

We maintain a strong growth mindset, with continuous development and learning as a priority.

If you are a skilled and ambitious scientist looking to take the next step in your career, joining Isomorphic Labs will lift you out of your comfort zone and provide you with an amazing opportunity for personal growth and development.

As part of the ongoing expansion of our Drug Design and Medical Research function, we are hiring Synthetic Chemists who are keen to impact medicinal chemistry projects and/or CMC projects. You will support the business alongside world-leading AI/ML Drug Design Platform teams. You will deliver scientific expertise and strategic direction to drive improvements in the Platform and the advancement of active drug discovery programs.

• Apply your Synthetic Chemistry expertise across Medicinal Chemistry and/or CMC projects.
• Act as a Synthetic Chemistry Lead in one or more active drug discovery programs.
• Collaborate both internally and with third party organisations, interacting within multidisciplinary teams to support the data-driven delivery of high quality scientific solutions to complex technical problems.
• Work cross-functionally with the Medicinal Chemistry, DMPK, Biology, and Technology teams.
• Represent the company externally, interacting with existing and prospective collaborators including Contract Research Organisations (CROs) and Contract Development & Manufacturing Organisations (CDMOs).
• Prepare detailed scientific proposals and reports to support new and ongoing programs.
• Embrace and champion our culture of inclusion and continuous professional development.

• PhD in Synthetic Chemistry, or a related technical field, or equivalent industrial experience.
• 3+ years professional experience in a Chemistry role, operating within a biotech, pharma or CRO setting. 5+ years' experience for more senior positions.
• Solid technical foundation in synthetic chemistry with previous experience operating independently as an individual contributor.
• Excellent problem-solving and decision-making capabilities applied to complex synthetic chemistry challenges.
• Experience of working with and closely managing CRO and/or CDMO resources.
• A genuine passion for drug discovery and enthusiasm for the potential of AI/ML to transform the field.
• Excellent communication (written and verbal) and interpersonal skills, with an ability to work effectively in a cross-functional, collaborative team environment.
• Track record of creative problem solving with a strong growth mindset,…