Senior Director, Portfolio Integration Lead

The Portfolio Integration Lead (PIL) is a senior role in Oncology Clinical Development. It shapes the advancement of multiple oncology programmes, focusing on specific cancers, and works closely with the VP, Clinical Development Leads (CDLs), and cross‑functional teams across GSK to ensure scientific alignment, portfolio coherence, and development excellence across assets.

• Provide senior scientific partnership to CDLs, especially in disease biology, biomarker strategy, and novel treatment combinations development.
• Ensure consistent cross‑programme ways of working to improve development efficiency and execution.
• Drive cross‑programme portfolio working groups and ensure business‑level alignment.
• Drive and support clinical trial innovation based on evolving oncology treatment landscape, regulatory changes, basic/translational science, and emerging technologies such as AI‑enabled tools.
• Strengthen the scientific and strategic positioning of a pan‑asset portfolio across multiple clinical and pre‑clinical assets.
• Drive initiatives that advance data and technology strategies supporting development decision‑making.
• Shape engagement with external experts and governance bodies, including advisory boards where relevant.

• Shape advancement of multiple development programs within the oncology portfolio by providing scientific insights across assets.
• Ensure agreed disease strategy is implemented consistently across programs.
• Prepare detailed strategic analyses and portfolio recommendations on behalf of the Disease Area Vice President.
• Co‑ordinate across Clinical Matrix Teams (CMTs) and stakeholders in Research & Development (R&D), Global Medical Affairs (GMA), and Global Product Strategy (GPS).
• Drive disease‑level strategic discussions and portfolio planning at governance discussions and prioritisation.
• Serve as a subject‑matter expert supporting global health authority interactions, regulatory submissions, and key development milestones across multiple assets.

• Serve as a scientific thought partner to CDLs across multiple asset programs, shaping key aspects of clinical development strategy.
• Contribute to disease biology, translational science, biomarker and precision medicine approaches, combination strategies, and emerging clinical development opportunities.

• Establish and champion consistent ways of working across programs to improve efficiency and development quality.
• Drive innovation in clinical development approaches for a given disease area, including trial design, novel endpoints, and emerging technologies such as AI‑enabled analytics.

• Maintain deep understanding of evolving tumour disease landscape, standards of care, and emerging science.
• Shape engagement with external experts through advisory boards and synthesize portfolio‑level external insights to strengthen development strategy.

• Drive initiatives that strengthen application of data, technology, and analytics in clinical development decision‑making for a given tumour type.
• Champion innovative approaches to clinical trials and portfolio insights, ensuring the tumour portfolio remains at the forefront of emerging capabilities.

• Minimum education:
  
  Bachelor’s, Master’s, or advanced degree in a scientific or medical discipline.
• Experience in oncology drug development within pharmaceutical or biotechnology environments, including work across multiple programs or assets.
• Experience with clinical development processes, regulatory pathways, and oncology therapeutic landscapes.
• Experience operating in structured matrix organizations and demonstrating decision‑making and stakeholder engagement at senior organisational levels.
• Experience as a Clinical Development Lead, Medical Director, Clinical Scientist Program Lead, or equivalent program leadership role in oncology.
• Expertise in biomarker development, precision medicine strategies, or combination therapy approaches.
• Experience engaging with external scientific experts, advisory groups, and Health Authorities.
• Demonstrated ability to influence senior stakeholders and shape strategic portfolio discussions.
• Familiarity with clinical trial innovation methods, including AI/ML applications, adaptive trial designs, or real‑world evidence integration.

GSK is an Equal Opportunity Employer.