Protein Production Scientist, Biologics

LEVEL:
Scientist / Senior Scientist
·

LOCATION:

London (20 Triton Street)
· PATTERN:
In-person, lab-based

We are building the protein production cascade that turns a sequence into characterised, quality-controlled protein at scale, and you will build it from the first manual run. This is the work upstream of every protein data point we generates: DNA design, molecular biology, protein expression, purification, and quality control, developed by hand and engineered to move onto automation.

AI for biology has a data problem. The data that matters most doesn’t exist yet, so we’re building the infrastructure to produce it, with quality and traceability built in from day one.

We’re in stealth and heads-down on execution. We’ll share more about what we’re building once you’ve spoken with the team.

You will build the protein production cascade that sits upstream of molecular characterisation and functional assays: DNA design, molecular biology, protein expression, purification, and quality control through analytical characterisation. The cascade will eventually run autonomously on our automation platform. In the first phase, you develop each step by hand, running protocols manually, setting reproducibility and quality thresholds, and proving each phase works before it moves onto instrumentation.

As the automation platform comes online, the work shifts toward instrumented execution, equivalence validation, and the engineering judgement calls that decide which manual steps get automated and which stay in human hands. You will work directly with the automation engineering and software teams on the boundary between scientific protocols and autonomous execution, at Scientist or Senior Scientist level, alongside Principal Scientists at the bench, and you will grow into protocol authorship over the first year.

• Land in the lab. Set up your bench at the London site and start manual assay development alongside a senior member of the protein sciences vertical.
• Get hands on the first priority protein production workflows as the day-one assay menu locks.
• Start building DNA design and production (linear DNA), protein expression (cell-free), and protein purification and QC at high throughput. Run them by hand on equipment that will eventually move onto the automation platform, capturing the data-structure and metadata decisions that translate into automation design.
• Build reproducibility, precision, and acceptance thresholds into the workflow.
• Contribute to the day-one menu decisions and begin authoring SOPs for your slice of the assay portfolio. Help interview the scientists and lab technicians joining alongside you.

• Have a linear DNA, cell-free expression, purification, and QC workflow in a semi-automated state, running at the scale of hundreds to thousands per week and ready for full automation.
• Co-design protocols with the software and automation engineering teams so the manual versions you validate are automation-ready by design. Decide which manual judgement calls have to be engineered out before they reach the platform.
• Start building DNA design and production (plasmid DNA), protein expression (mammalian), and protein purification and QC at high throughput, again by hand on equipment that will move onto the platform.
• Build reproducibility, precision, and acceptance thresholds into the workflow.
• Contribute to co-design conversations with the first commercial customers, including the foundation-model partners coming online from 2027.

• Workcells arrive in the lab. Move the validated assays onto them, running with instrumentation and human intervention in the loop.…