Postdoctoral Research Associate in MALDI Imaging Mass Spectrometry

** What You Will Do*
* ** Overview*
* Los Alamos National Laboratory (LANL) Bioscience Division, Biochemistry and Biotechnology Group (BTEK) is seeking a Postdoctoral Research Associate to advance MALDI imaging mass spectrometry (IMS) methods and data workflows. This role focuses on spatially mapping biomolecules across diverse sample types and translating IMS data into actionable biological insight. The successful candidate will contribute to mission-driven research with national security applications (e.g., molecular signatures of radiation exposure and other biosecurity/bioenergy priorities).

You will work in a highly collaborative environment with access to state-of-the-art high-resolution mass spectrometers (including multiple Orbitrap platforms) and robust high-performance computing resources. The position includes opportunities to publish in high-impact journals and present at conferences.

Key Responsibilities

+ Develop, optimize, and apply MALDI IMS sample-preparation and acquisition methods for targeted and discovery spatial analyses.

+ Build and/or improve IMS data processing, visualization, and interpretation pipelines, including spatial statistics where appropriate.

+ Collaborate with multidisciplinary teams to integrate IMS outputs with complementary measurements and biological context.

+ Implement and document quality control approaches appropriate for IMS studies (reference standards, process controls, and system-performance checks).

+ Communicate results through peer-reviewed publications, technical reports, and conference presentations.

** What You Need*
* Minimum

Job Requirements:

-  Ph.D. in a STEM field completed within the last five years (or expected by the start date).

-  Strong peer-reviewed publication record commensurate with career stage.

-  Demonstrated excellence in written and oral communication (e.g., manuscripts, reports,

presentations).

-  Deep understanding of mass spectrometry fundamentals and
-omics pipeline concepts.

-  Hands-on experience spanning sample preparation, instrument operation/data acquisition, and data

analysis.

-  Ability to obtain a DOE Q clearance (typically requires U.S. citizenship).

Desired

Qualifications:

+ Demonstrated experience with MALDI IMS data processing, spatial visualization, and interpretation.

+ Experience developing reproducible computational workflows (e.g., scripting, version control,documented pipelines).

+ Familiarity with statistics and/or machine learning methods for robust molecular panel

Development.

+

Experience with multi-omics harmonization and integration is a plus.

+ Experience designing and executing QC plans (reference/quantitative/process/system-performance controls).

Essential Job Functions (can perform with or without reasonable accommodation):

Work Environment:

Work Location:

The work location for this position is onsite and located in Los Alamos, NM. All work locations are at the discretion of management.

Work Schedule

This position is located in Los Alamos, NM. Candidates may work a 9/80 schedule at the discretion of management and in accordance with the Postdoc Program Resource Guide. Initial appointment is for two years; a third year may be possible based on performance and programmatic need. Exceptional candidates may be considered for LANL Director's Fellowships and named fellowships

Note to Applicants:

Required Application Materials

+ Current resume/CV

+ Current official transcripts

+ Cover letter/personal statement of interest, not to exceed one page

Due to federal restrictions contained in the current National Defense Authorization Act, citizens of the People's Republic of China-including the special administrative regions of Hong Kong and Macau-as well as citizens of the Islamic Republic of Iran, the Democratic People's Republic of Korea (North Korea), and the Russian Federation, who are not Lawful Permanent Residents ("green card" holders) are prohibited from accessing facilities that support the mission, functions, and operations of national security laboratories and nuclear weapons production facilities, which includes Los Alamos National Laboratory.

** Where You Will Work*
* Located in beautiful northern New Mexico, Los Alamos National Laboratory (LANL) is a multidisciplinary research institution engaged in strategic science on behalf of national security. Our generous benefits package includes:

+ PPO or High Deductible medical insurance with the same large nationwide network

+ Dental and vision insurance

+ Free basic life and disability insurance

+ Paid childbirth and parental leave

+ Award-winning 401(k) (6% matching plus 3.5% annually)

+ Learning opportunities and tuition assistance

+ Flexible schedules and time off (PTO and holidays)

+ Onsite gyms and wellness programs

+ Extensive relocation packages (outside a 50 mile radius)

** Additional Details*
* Directive 206.2 - Employment with Triad requires a favorable decision by NNSA indicating employee is suitable under NNSA Supplemental Directive 206.2…