Integrated Safety Analysis; ISA Engineer

Integrated Safety Analysis (ISA) Engineer

About the Company

General Matter is enriching uranium in America.

Our mission is to restore our country’s ability to make nuclear fuel. Our fuel will help power AI, manufacturing, and other critical industries. It will power our next generation of reactors. Ultimately, it will power our national ambitions.

We were incubated by Founders Fund, like Anduril and Palantir before us, and we are backed by top tier investors.

Our lean, world-class team of engineers and operators is applying a first-principles approach to solving the problem of nuclear fuel production.

We are a mission-driven company with a culture of urgency, accountability and transparency.

We are seeking a highly skilled Integrated Safety Analysis (ISA) Engineer to support the design, licensing, and operation of a new Nuclear Regulatory Commission (NRC)–licensed fuel enrichment facility regulated under 10 CFR Part 70. In this role, you will be a key contributor to ensuring that plant processes meet regulatory requirements for nuclear criticality safety, chemical safety, fire protection, and overall facility risk management.

The ideal candidate has experience working in nuclear or high-hazard industries, strong analytical skills, and a deep understanding of risk‑informed safety methodologies.

• Lead and support development of Integrated Safety Analyses (ISAs) in accordance with 10 CFR Part 70 Subpart H, including hazard identification, accident sequence modeling, and consequence analysis.
• Perform and document process hazard analyses (PHAs) using techniques such as HAZOP, What‑If, and FMEA.
• Develop, evaluate, and maintain items relied on for safety (IROFS) and associated safety controls.
• Work closely with engineering, operations, and regulatory teams to ensure plant design, modifications, and procedures remain compliant with NRC licensing basis.
• Develop and maintain ISA Summary documentation, safety basis changes, and supporting technical analyses.
• Support NRC interactions, including audits, inspections, and technical review responses.
• Conduct risk assessments related to nuclear criticality safety, chemical hazards, fire protection, and facility natural phenomena hazards.
• Participate in configuration management, change reviews, and design verification for modifications impacting the facility safety basis.
• Provide technical expertise to support startup, commissioning, and operational readiness activities.

• Bachelor’s degree in Chemical Engineering, Mechanical Engineering, Nuclear Engineering, or a related field. Advanced degrees (MS, MBA, or PhD) may substitute for up to 2-3 years of experience, depending on the degree level.
• 4+ years of experience in nuclear safety, process safety, or similar high‑hazard environments.
• Familiarity with safety analysis methodologies, for example:
  • Process Hazard Analysis (PHA)
  • Criticality Safety Analysis (CSA)
  • Fire Hazard Analysis (FHA)
  • External Hazard Analysis (EHA)
• Strong analytical and problem‑solving abilities, with attention to detail.
• Excellent communication skills, both written and verbal, for conveying technical safety data to diverse audiences.
• Ability to work collaboratively across engineering, operations, and licensing teams.

• Evidence of exceptional ability (prior projects, portfolio of work, completed products, etc).
• Experience in a fast‑paced engineering environment or a highly technical role requiring a resourceful, entrepreneurial approach to complete tasks within tight time frames or budget constraints.
• Experience with IROFS, ISA, ISA Summaries, Safety Analysis Reports (SAR), HAZOP, and Risk Determination.
• 8+ years of experience in nuclear safety, process safety, or similar high‑hazard environments.
• Direct experience with the NRC 10
  
  CFR
  70 license application process.
• Familiarity with NRC safety standards and relevant regulatory frameworks.
• Knowledge or experience with vacuum systems, cryogenics, compressible flow, or nuclear chemical processes.
• In lieu of nuclear related experience, a strong preference will be given to candidates with petrochemical ISA engineering experience.

• Abi…