Associate Director, Portfolio Operations and Insights

Associate Director, Portfolio Operations and Insights

US Remote

The Associate Director of R&D Portfolio Operations & Insights will drive the design, standardization, and continuous improvement of portfolio management processes across the R&D organization.

This role is responsible for enabling integrated planning, improving predictability, and driving portfolio transparency through scalable PMO frameworks, data infrastructure, analytics, and reporting - including robust financial modeling, budget governance, and investment performance tracking. This individual will serve as a strategic operations partner to R&D, Finance, and PMO Leadership, ensuring there is a single-source of truth to enable portfolio insights and decisions.

• Design and implement standardized PMO processes, tools, and governance frameworks across R&D.
• Establish integrated planning processes that connect strategy, resource planning, timelines, and execution milestones.
• Drive adoption of best practices for stage-gate governance, risk management, and cross-functional alignment.
• Lead continuous improvement initiatives to enhance operational rigor, predictability, and accountability.

• Establish phase-appropriate budget frameworks for projects at each stage-gate, defining level of estimate rigor
• Define and maintain a standardized process for project budget creation, baseline-setting, and adjustment ensuring consistency in how budgets are structured and tracked across the portfolio
• Implement mechanisms to measure and report budget adherence at the project level, including variance analysis, earned value metrics, and escalation thresholds for material deviations
• Partners with Finance to align on capitalization and expense treatment, ensure accurate project cost coding and support close and accrual processes
• Support business case development by providing standardized templates NPV/ IRR modeling, and scenario analysis
• Own and evolve the R&D portfolio management database, ensuring data accuracy, integrity, and usability.
• Define data standards, KPIs, and portfolio health metrics including financial KPIs such as cost-to-market, forecast accuracy, and budget accuracy.
• Lead vision for automated dashboards and trending analyses to provide real-time insights to leadership.
• Enable scalable reporting capabilities through tools and systems optimization.
• Create portfolio views to support investment decisions, resource allocation, and strategic trade-offs.
• Work with PMO portfolio leads to develop executive-ready reporting packages (monthly/quarterly) highlighting progress, risks, financial performance and trends.
• Translate complex data into clear, actionable insights for senior stakeholders.

• Bachelor’s degree in Biology or equivalent. MS or PhD in Biological Sciences preferred.
• Minimum of 10 years of program management experience in biotech space and educational background in molecular biology or genetics testing.
• Experience as FP&A or Finance Manager supporting Engineering or Product organizations desirable.
• Certification or formal training in Program or Project Management and experience using resource management tools is a big plus.

• Strong knowledge of creative workflows, project management tools and processes.
• Experience compiling GANTT charts and project plans.
• Experience with product development.
• Familiar with design control is a plus.
• Proficiency in financial modeling, budget management, and portfolio financial analysis; experience with NPV, cost-to-market, and forecast accuracy methodologies.
• Comfort working with large datasets and financial systems; experience with portfolio management platforms (e.g., Planisware, Smartsheet, Oracle, SAP) and BI tools (e.g. Tableau, Power BI) is a plus.
• Excellent interpersonal skills and the ability to establish and build productive relationships.
• Excellent communication within the project teams as well as with diverse stakeholders, including top level management.
• Excellent organization and time management/multi-tasking skills (comfortable in an ambiguous and fast-paced environment, operating at both strategic and…