Chemistry Lead

About the Company

General Matter enriches uranium.

We are designing, building, and operating the world’s lowest-cost enrichment services, here in the US.

In the process, we are restoring America’s ability to produce nuclear fuel to power AI, advanced manufacturing and critical industries our country relies on to remain competitive.

Fuel drives the cost of advanced reactor electricity production, and enrichment drives the cost of the fuel that advanced reactors consume. Reliable, low-cost enrichment is the catalyst for the nuclear Renaissance now under way.

Our mission is to make nuclear not only the cleanest and safest source of baseload power, but also the most affordable. We believe abundant nuclear energy will lead to a post-scarcity society.

We were incubated inside Founders Fund, like Anduril and Palantir before us, and are backed by over a dozen of the world's top venture capital firms.

Our lean, world-class team of engineers and operators is applying a first-principles approach to solving the problem of nuclear fuel production.

We are a mission-driven company with a culture of urgency, accountability, and transparency.

Help us build a high-energy society by making the cleanest, safest form of baseload energy the most affordable.

As Chemistry Lead at General Matter, you'll build and lead the analytical chemistry capabilities that enable our advanced uranium enrichment operations from the ground up. You'll establish laboratory methods, quality systems, and team processes that directly support production operations, NRC compliance, and nuclear material accountability. This is a rare opportunity to shape chemistry operations at a next‑generation nuclear facility during rapid commercial scale‑up, where your technical decisions immediately impact our ability to strengthen domestic nuclear fuel supply.

• Oversee materials testing activities to support project and operational needs
• Develop, validate, and implement analytical methods for material characterization and quality control; establish SOPs for testing protocols, sample handling, data documentation, and reporting standards.
• Ensure laboratory compliance with quality assurance requirements, safety protocols, and regulatory expectations; implement quality control procedures including method validation, measurement uncertainty analysis, and audit readiness.
• Manage laboratory operations including equipment maintenance, calibration, inventory management, sample queue prioritization, and vendor coordination.
• Provide technical expertise to engineering, operations, and program management; interpret analytical data, conduct failure analysis, troubleshoot process chemistry issues, and deliver timely results.
• Partner with licensing and regulatory affairs teams to support NRC Part 70 compliance; provide analytical data, method descriptions, and technical interface for regulatory submissions and inspections.
• Support nuclear material control and accountability (MC&A) interfaces, including analytical methods for material accountancy, measurement control programs, and investigation of analytical anomalies.
• Develop capability roadmaps for analytical chemistry; assess equipment and personnel needs, manage external laboratory relationships, and scale operations to support company growth.
• Establish performance metrics, manage documentation systems, prepare technical reports for stakeholders, and support management reviews and audits.

• Ph.D. in analytical, inorganic, physical, radio-, or nuclear chemistry; OR M.S. with 5+ years experience; OR B.S. with 8+ years experience.
• 5+ years hands‑on analytical chemistry experience, with 2+ years in supervisory or laboratory management role.
• Demonstrated expertise in multiple analytical techniques: spectroscopy (FTIR, Raman, NMR, UV‑Vis), chromatography (GC, HPLC, IC), thermal analysis (DSC, TGA), mass spectrometry, XRD, or elemental analysis.
• Experience developing analytical methods, writing SOPs, implementing quality control programs, and maintaining laboratory compliance in regulated environments.
• Strong knowledge of laboratory instrumentation operation, maintenance, troubleshooting, and…