Chemical Development Trace Analysis Scientist

Overview

This is a full-time, permanent position offering a flexible 36.5 hour week, Monday – Friday. Visa sponsorship is not available. The role is for an enthusiastic and innovative Analytical Scientist, based at a world-class Pharmaceutical company facility in Macclesfield. The role focuses on drug substance development in the pharmaceutical industry.

• Develop, optimise and validate advanced trace analysis methods using LC-MS and Orbitrap technologies to detect and quantify trace-level small molecules in raw materials, intermediates and drug substances.
• Provide technical expertise to project teams, supporting assessment of mutagenic impurities, nitrosamines and other trace analytes at parts-per-billion levels.
• Perform complex analytical investigations, interpret scientific data and apply innovative problem-solving to deliver accurate, high-quality results for clients.
• Support and enhance trace analysis capabilities by sharing specialist knowledge, advising stakeholders and contributing to successful analytical programmes.
• Author and review key analytical documentation, including testing plans, method development reports and validation protocols (as appropriate).
• Collaborate effectively with multidisciplinary internal and external teams, communicating scientific concepts clearly while fostering technical excellence and continuous improvement.

• Degree or higher qualification in Chemistry, Analytical Chemistry or a related scientific discipline, with a strong foundation in organic chemistry and analytical science.
• Pharmaceutical analytical experience within a development laboratory environment, with knowledge of drug development processes and analysis of raw materials, intermediates and drug substances.
• Hands-on experience developing and applying advanced analytical techniques, including LC-MS/MS, GC-MS/MS, GC-HRMS and LC-HRMS; experience with NMR, IC or ICP-MS is advantageous.
• Strong troubleshooting and problem-solving skills; ability to investigate analytical and instrumentation issues and develop effective technical solutions.
• Good understanding of GMP requirements and experience with electronic systems and Microsoft Office; excellent documentation, organisational and data management skills.
• Excellent communication and relationship-building skills; ability to work independently and collaboratively, adapt to changing priorities and demonstrate commitment to quality, customer service and continuous improvement.

• Reward and Recognition Scheme for great work
• Holiday entitlement increases with service
• Option to join Health Cash Plan for routine healthcare expenses
• Life Assurance from day one (four times annual salary)
• Automatic enrolment into Company Pension Plan after three months (opt-out available)
• Access to Employee Assistance Programme (24/7 confidential support)
• Volunteering opportunities during working hours
• Free on-site car parking
• Opportunities to explore worldwide assignments
• Perkbox access with various savings and lifestyle benefits

Our people are the backbone of what we do. You will be invited to meet the team through an assessment centre or a staged interview process depending on the role.