Senior Director, Chief of Staff - Global Business Unit

Working with Us

Challenging. Meaningful. Life-changing. Those aren’t words that are usually associated with a job. But working at Bristol Myers Squibb is anything but usual. Here, uniquely interesting work happens every day, in every department. From optimizing a production line to the latest breakthroughs in cell therapy, this is work that transforms the lives of patients, and the careers of those who do it.

You’ll get the chance to grow and thrive through opportunities uncommon in scale and scope, alongside high-achieving teams. Take your career farther than you thought possible.

Bristol Myers Squibb recognizes the importance of balance and flexibility in our work environment. We offer a wide variety of competitive benefits, services and programs that provide our employees with the resources to pursue their goals, both at work and in their personal lives. Read more:

The Senior Director, Chief of Staff serves as a strategic advisor, operational leader, and execution partner to the Senior Vice President, Global Business Unit. The role is accountable for driving strategic alignment, governance, execution excellence, organizational effectiveness, and enterprise-wide coordination across the Global Business Unit.

The incumbent leads the development and execution of operating mechanisms that translate business strategies into measurable outcomes while ensuring alignment with enterprise objectives. The role acts as a central integrator across site Strategy & Operations organizations, Quality, Manufacturing, Supply Chain, Finance, Human Resources, Digital, Technical Operations, and other key business functions to ensure effective decision-making and flawless execution.

This position is responsible for establishing governance frameworks, leading strategic planning activities, driving risk identification and mitigation processes, overseeing performance management systems, and ensuring operational excellence across complex global initiatives.

The Senior Director, Chief of Staff must ensure that activities supporting GMP-regulated operations are conducted in compliance with applicable regulatory requirements, Quality Management System (QMS) standards, data integrity principles, company policies, and current Good Manufacturing Practices (cGMPs). The incumbent must comply with all Security, Environmental Health & Safety, Privacy, and Compliance requirements applicable to the position.

New Jersey (New Brunswick, Lawrenceville, Giralda Farms) or Massachusetts (Devens), USA;
Dublin, Ireland;
Boudry, Switzerland

• Strategic Direction & Business Execution
• Partner with the SVP, Global Business Unit to define, communicate, and execute strategic priorities aligned with enterprise objectives.
• Lead development of annual business plans, long-range strategies, organizational priorities, and execution roadmaps.
• Translate strategic objectives into measurable deliverables, governance processes, and accountability.
• Support executive decision-making through analytics, business insights, scenario planning, and strategic recommendations.
• Drive strategic alignment across leadership teams to ensure effective prioritization of resources, investments, and organizational initiatives.
• Lead preparation of executive reviews, business updates, leadership presentations, and Board-ready materials as required.

• Cross-Functional Leadership & Multi-Site Coordination
• Partner with Site Strategy & Operations leaders to align strategic priorities, coordinate execution activities, and ensure consistency across locations.
• Lead and influence cross-functional teams responsible for enterprise initiatives, transformation programs, productivity efforts, and business-critical deliverables.
• Coordinate complex, multi-site responsibilities and drive resolution of cross-functional issues impacting business objectives.
• Facilitate collaboration among Quality, Manufacturing, Supply Chain, Finance, Human Resources, Digital, Engineering, and Technical Operations organizations.
• Establish operating mechanisms that improve accountability, visibility, and execution effectiveness across the Global Business Unit.

• Governance, Risk Management & Organizational Performance
• Develop and maintain governance processes supporting business execution, operational reviews, strategic programs, and leadership decision-making.
• Define and monitor key performance indicators (KPIs), metrics, dashboards, and management reporting systems.
• Manage strategic business reviews and performance assessments to ensure achievement of organizational goals.
• Develop and implement proactive risk management strategies, including identification, assessment, mitigation, escalation, and monitoring of risks.
• Lead issue resolution, contingency planning, and business continuity activities supporting critical business operations.
• Ensure governance practices align with internal controls, regulatory requirements, and organizational policies.

• Operational Excellence & Continuous Improvement
• Drive…