Associate Director, Oncology Clinical Biomarker Asset Lead, Translational Development

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Bristol Myers Squibb has pioneered the development of immuno-oncology therapies and continues to diversify in drug development for the treatment of cancers. Our world-class Translational Development organization is exploring new aspects of tumor and immune biology to create tailored, individualized treatment strategies that will offer the greatest possible benefit to patients.

The Clinical Biomarker Asset Lead role will be responsible for development and execution of translational strategies in solid tumor oncology for assigned programs. Key responsibilities of this role are to act as a lead scientist to implement and deliver on biomarker strategies for clinical programs, develop reports and publications on translational data generated to support asset development and contribute to regulatory submissions.

This individual will work on cross-functional project teams to drive execution of translational/biomarker plans working with disease and lab scientists, as well as BMS members from clinical, medical, commercial, regulatory, and diagnostics. Individual will also engage with external academic collaborators/Key Opinion Leaders (KOLs).

• Integrate translational research and clinical development, developing biomarker strategies in alignment with clinical development objectives, leading efforts for data generation and interpretation and for communication to the development teams.
• Responsible for understanding external research environment, partnering with other functions both internally and externally to coordinate the execution of Translational development deliverables.
• Engages functional groups to develop, champion, implement and align biomarker strategies for development projects in support of the overall R&D portfolio goals.
• Effectively engages with teams and matrix leadership to define, revise and progress translational biomarker plans.
• Continually analyzes progress, engages in critical thinking, and asserts strong problem-solving towards delivering key data and interpretations essential for decision making.
• Delivers high quality biomarker strategies for understanding mechanism of action/resistance, target engagement, pharmacodynamics endpoints and patient selection.
• Ensures the output of the biomarker plans meets established project standards.
• Engages team members to ensure alignment of biomarker strategies with clinical operational plans and with functional area capabilities to execute and deliver on robust translational biomarker data package to support trial and program
• Builds productive relationships with team members that interact with the translational clinical biomarker group.
• Effectively interfaces with functional areas to ensure strategic alignment and to identify resources needed to deliver on biomarker goals
• Productively engages with external collaborators and scientific KOLs to support translational goals.
• Communicates key biomarker program information, risks, and milestones, and manages information flow across team members

• Ph.D. in Oncology/immunology or related field with
• 5-8+ years of industry experience
• 3-5 years in oncology/biomarkers/translational or correlative research
• Previous experience as Biomarker Lead for late-stage clinical trials;
  Experience in phases II/III required
• Requires comprehensive knowledge of principles, concepts and / or methodologies within drug discovery or clinical development
• Has significant understanding of the role of translational research/medicine and clinical biomarkers in drug development
• Demonstrated knowledge of oncology and/or tumor-immunology disease biology
• Regulatory submissions drug approvals in solid tumor space also highly desirable
• In-depth understanding of solid tumor oncology with knowledge of current and evolving clinical landscape and competitive scenarios
• Strong scientific background with understanding of clinical, translational, and mechanistic data with proven track record of publications
• Understanding of early or late-stage drug and translational development process; including experience with implementing a biomarker strategy
• Clinical…