Senior Manager, Full Stack Software Engineering & Operations Regulatory BI&T

Working with Us

Challenging. Meaningful. Life-changing. Those aren't words that are usually associated with a job. But working at Bristol Myers Squibb is anything but usual. Here, uniquely interesting work happens every day, in every department. From optimizing a production line to the latest breakthroughs in cell therapy, this is work that transforms the lives of patients, and the careers of those who do it.

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Position Summary:

We are seeking a Senior Manager, Full Stack Software Engineer, to serve as a technical leader in an AI first, agile product environment supporting Global Regulatory Sciences (GRS) technologies. This role is accountable for the end-to-end build and run of AI-native technology assets supporting Global Regulatory Sciences, ensuring solutions are reliable, accessible, secure, compliant, and cost-effective.

The Senior Manager designs, builds, and operates AI native products where large language models, agentic workflows, and data-driven intelligence are the default paradigm-not an addon. The role blends hands-on full-stack engineering, AI product thinking, and operational ownership, with responsibility for both delivery and long-term‑ sustainability of platforms in a regulated Bio Pharma environment.

This position provides cross-product technical leadership without direct line management, influencing architecture, shared capabilities, vendor direction, and long-term technical strategy through expertise, collaboration, and hands-on contribution.

Key Responsibilities:

AI Native‑ Product & Platform Ownership:

* Own the build, operation, and continuous improvement of AI native Regulatory applications and platforms, including bespoke solutions and AI-enabled SaaS.

* Ensure Regulatory technology assets are stable, secure, compliant, and operationally sound across their lifecycle.

* Remain sufficiently hands-on‑ to design, build, review, and troubleshoot critical components.

Technical Strategy, Architecture &

Roadmap:

* Develop and maintain an AI-first‑ Regulatory technology roadmap, guiding build vs. buy decisions, model selection, and platform capabilities aligned to business outcomes.

* Define and enforce reference architectures, reusable patterns, and technical guardrails to ensure consistency and quality across products.

* Evaluate emerging technologies and delivery models (SaaS / PaaS / IaaS) and influence vendor roadmaps and negotiations to align with enterprise strategy.

Engineering Execution & Operations:

* Design, develop, and operate scalable, secure full stack solutions using Python, Java / Node.js, React, REST APIs, and modern cloud-native architectures.

* Design and operate Large Language Model LLM native and agentic systems as long-lived products, incorporating human‑ in‑ the-loop, monitoring, governance, and continuous improvement.

* Build and maintain ML and data pipelines for training, validation, deployment, monitoring, retraining, and rollback.

* Implement CI/CD practices and automate workflows across data ingestion, feature engineering, model versioning, and deployment.

* Diagnose and resolve complex technical issues, balancing short-term remediation with long-term‑ architectural strategy.

Product, Stakeholder & Vendor Partnership:

* Partner closely with IT Product Managers and GRS stakeholders to plan, prioritize, deliver, and support strategic digital capabilities.

* Translate business needs into well designed technical solutions that drive measurable impact in regulatory and operational workflows.

* Operate effectively in a highly matrixed organization, aligning stakeholders with differing priorities.

Financial & Operational Stewardship:

* Manage and optimize Total Cost of Ownership (build and run) for technology assets,…