R&D Project Manager Job Madison area,Wisconsin USA,Management

R&D Project Manager

Histo Sonics is a commercial-stage medtech company advancing the Edison® System, a novel non-invasive sonic beam therapy based on histotripsy. Since receiving FDA De Novo grant for the non-invasive destruction of liver tumors in 2023, the company has progressed beyond initial market entry into commercial expansion, reimbursement momentum, and ongoing clinical and pipeline development. In addition to its current liver tumor indication, Histo Sonics is pursuing future indications across multiple applications including kidney, pancreas, prostate, neuro, women's health, and other significant underserved human health areas, to realize the broader potential histotripsy across multiple disease states and medical specialties.

Location:

Plymouth, MN (preferred);
Madison, WI; or Ann Arbor, MI

Position Summary (Why this role matters):

The R&D Project Manager is a dedicated operational partner to an R&D Program, responsible for managing the full scope of project coordination and execution for their assigned Program. Histo Sonics' Programs focus on early feature definition, technical investigation, and de-risking, encompassing multiple feature and technology work streams executing in parallel at various stages (feasibility, definition, on-deck, and implementation) in preparation for formal integration into the product.

This role manages the operations and coordination of all Program activities and partners with the Program Director that focuses on roadmap strategy, feature prioritization, clinical and technical insight synthesis, and cross-program alignment.

This role reports to the Director of R&D Pipeline and Portfolio Management to ensure consistent methodology and portfolio visibility, while dedicating most of their time to their assigned Program's needs. A core part of this role is ensuring that Program outputs — de-risking status, open risks, and documented findings — are tracked with enough rigor and transparency to inform Project scope decisions and facilitate handoff to System Integration Project teams.

Depending on Program assignment and business need, this role may also support portfolio-level project management for the Director of R&D Pipeline and Portfolio, including communication of project updates, resource analysis, and portfolio visibility.

Key Responsibilities (What you'll do):

Program Operations & Coordination

Own the assigned Program's operational cadence: maintain the master schedule or feature tracker, facilitate team status meetings, manage action tracking, and drive accountability across the cross-functional team. Ensure Program documentation remains current, accessible, and consistent with Histo Sonics' design control standards.
Maintain current and accurate status across the Program's tracked features and work streams — progress, priorities, risks (execution, technical, and patient safety), resource allocations and hiring plans, and target dates — flagging risks and priority constraints to the Program Director and Director of R&D Pipeline and Portfolio.
Coordinate logistics needed to keep the Program moving — which may include hardware deployment and build status, lab scheduling, resource allocations, or kickoff readiness for upcoming work streams, depending on the Program's needs.
Partner with the Program Director to ensure new feature readiness is represented accurately to the Director of R&D Pipeline and Portfolio ahead of Project scope decisions, supporting credible scenario modeling of what is ready, and support a clean handoff of scoped features to the System Integration Project team.

External Partner & Cross-Functional Coordination

For Program activities involving external development partnerships, act as the operational point of contact by managing partner meeting cadences, preparing agendas and pre-reads, documenting decisions and action items, and tracking deliverables against commitments. Coordinate requirements handoffs between the Program team and these partners or internal cross-functional owners, ensuring the Program Director's direction is clearly operationalized in their workplans.
Monitoring external and cross-functional partners' progress, proactively…