Senior Scientist , Molecular Biology​/Microbiology

Job Description

We are seeking a Senior Scientist I with a background in molecular biology and/or microbiology to join our peptide display hit generation team. In this role, you will lead and manage technology development projects and therapeutic peptide hit generation efforts.

• Lead the development of in‑house peptide display workflows (mRNA‑display and/or phage‑display) using our proprietary peptide microarray platform to accelerate hit identification. Design and generate display libraries, screen peptide libraries against therapeutic targets, perform next‑generation sequencing and conduct large‑scale data analysis.
• Explore and assess advanced technologies for modifying peptide display libraries, such as chemical modification and incorporation of non‑canonical amino acids.
• Use proprietary data analysis tools to efficiently analyze next‑generation sequencing data and other large‑scale datasets derived from peptide display libraries.
• Routinely demonstrate scientific initiative and creativity in research and development activities.
• Work highly autonomously in laboratory research or method development, requiring minimal direction from or interaction with a supervisor.
• Formulate conclusions and design follow‑on experiments based on multidisciplinary data.
• Initiate new areas of investigation that are scientifically meaningful and can be incorporated into a research or development plan.
• Be the primary author of publications, presentations, regulatory documents, and/or primary inventor of patents.
• Effectively communicate results and conclusions to a wide range of target audiences.
• Demonstrate high proficiency across a wide range of relevant techniques and technologies.
• Maintain a high level of efficiency and productivity. Adhere to timelines.
• Understand and adhere to corporate standards regarding code of conduct, safety, appropriate handling of materials, and controlled drug and radioactive compounds where applicable.

• Bachelor’s degree and 10 years of experience, Master’s degree and 8 years of experience, PhD with no experience required. Degrees should be in Molecular Biology, Microbiology, Biochemistry, Chemical and Biological Engineering, or other relevant fields.
• Thorough knowledge of chemical biology principles as they relate to the structure and function of peptides, proteins, and other biomolecules.
• Experience with mRNA‑display and/or phage‑display libraries, including design and generation, screening processes, and subsequent data analysis.
• Proficiency in generating next‑generation sequencing (NGS) libraries and analyzing the resulting sequencing datasets.
• Coding skills relevant to data science (e.g., Python) or a demonstrated willingness to learn such skills.
• Demonstrated ability to learn, understand and master new experimental techniques.
• Ability to multitask and work within timelines.
• Effective writer and communicator of research.

• Experience with incorporation of non‑canonical amino acids in mRNA‑display or phage‑display libraries.
• Experience in peptide therapeutics discovery and development.
• Experience with automation for scaling molecular biology/microbiology workflows.

• Compensation range: the range of possible base pay compensation that the Company believes in good faith it will pay for this role at the time of this posting based on the job grade for this position. Individual compensation paid within this range will depend on many factors including geographic location, and the Company may ultimately pay more or less than the posted range.
  
  This range may be modified in the future.
• Benefits: a comprehensive package of benefits including paid time off (vacation, holidays, sick days), medical/dental/vision insurance and 401(k) to eligible employees.
• Short‑term incentive programs: this job is eligible to participate in our short‑term incentive programs.

Note:

No amount of pay is considered to be wages or compensation until such amount is earned, vested, and determinable. The amount and availability of any bonus, commission, incentive, benefits, or any other form of compensation and benefits that are allocable to a particular employee remain in the Company’s sole and absolute discretion until paid and may be modified at the Company’s sole and absolute discretion, consistent with applicable law.

Abb Vie is an equal opportunity employer and is committed to operating with integrity, driving innovation, transforming lives and serving our community. Equal Opportunity Employer / Veterans / Disabled.