Cryo-EM Scientist

Cryo-Em Scientist

The UW-Madison Cryo-EM Research Centers comprise two facilities, the UW-Madison Department of Biochemistry Cryo-EM Research Center and the NIH-funded Midwest Center for Cryo-ET. Together, these Centers house state-of-the-art cryo-electron microscopy (cryo-EM) and cryo-electron tomography (cryo-ET) instrumentation. These technologies support bioscience researchers from academia and government, and private industry.

The Cryo-EM Scientist will be responsible for training new center users; operations of the instruments on behalf of users; developing advanced analytical techniques on behalf of the centers; staying abreast of advances within the community in order to incorporate those techniques within the centers; and representing the centers within the broader community at meetings, conferences, exhibits, and through peer-reviewed publications. This position is an excellent opportunity for an individual to work with cutting-edge instrumentation for Cryo-EM, cryo-ET, micro-ED, and cryo-FIB milling in state-of-the-art Cryo-EM research facilities.

Ideally, we are looking for a colleague with previous EM, Cryo-EM, light microscopy, or structural biology experience. There are ample opportunities for team training in all Cryo-EM modalities. This Cryo-EM Scientist will work with other center scientists as a team to support the missions of the Cryo-EM research centers. However, this individual should be self-motivated and able to work independently on a range of projects and tasks.

This Cryo-EM Scientist will join a team of scientists and administrative staff to support the growing Cryo-EM research resources and community at UW-Madison.

This is a full time, 100%, ongoing/renewable appointment. Normal hours are 7:45am – 4:30pm, Monday through Friday. Occasional nights and weekends may be required for this position.

• Attends and assists with the facilitation of scholarly events and presentations in support of continued professional development and the dissemination of research information
• Collects and analyzes research data, conducts experiments and interviews, and documents results according to established policies and procedures under general supervision and limited responsibility
• Assists with the identification of research problems and the development of research methodologies and procedures
• Serves as a main point of contact and liaison with internal and external stakeholders providing information and representing the interests of a specialized research area
• Conducts literature reviews, prepares reports and materials, and disseminates information to appropriate entities
• Writes or assists in developing grant applications and proposals to secure research funding

College of Agricultural and Life Sciences (CALS), Department of Biochemistry, Cryo-Electron Microscopy Research Center (CEMRC)

The minimum starting salary for a Scientist I is $65,000, and $75,000 for a Scientist II. However, final salary will depend on experience and qualifications. Employees in this position can expect to receive benefits such as generous vacation, holidays, and sick leave; competitive insurances and savings accounts; retirement benefits. Please review the summary of benefits for more information.

• Relevant research experience in the biological sciences that could include an understanding of cell biology, microbiology, protein biochemistry, or another appropriate sub-discipline.
• Experience with microscopy including light microscopy (fluorescence), electron microscopy, and/or cryo-electron microscopy.
• Experience with cryo-preparation techniques such as plunge-freezing, high-pressure freezing, cryo-microtomy, cryo-FIB milling, and other approaches.
• Demonstrated ability to effectively communicate and establish relationships with colleagues and collaborators in both oral and written forms of communication.
• A demonstrated ability to train or teach effectively.

• Experience in computational analysis of microscopy and/or Cryo-EM data.
• Basic familiarity with both tomographic and single-particle Cryo-EM methods.
• Experience in correlating images…