Senior Scientist II, Translational Biomarkers

The Position

This Senior Scientist will be part of a team responsible for delivery of translational biomarker strategies for drug development candidates. The ideal candidate will possess in-depth experience in translational research/medicine and clinical biomarkers in drug development. The candidate will also have strong communication skills, ability to work in a matrixed-based, fast paced environment, solid problem-solving abilities, and a commitment to excellence.

• Design, develop, and execute robust "fit-for-purpose" clinical biomarker assays to support the evaluation of pharmacodynamics, and prediction of clinical response.
• Identify and evaluate new technologies to support our evolving translational biomarker strategies.
• Partner with outsourcing functions to evaluate new CROs, drive transitioning and monitoring internally developed assays to external vendors.
• Effectively collaborate in a highly matrixed organization to drive advancement of early-stage projects into translational and clinical development.
• May lead Associate Scientists as a manager or mentor.
• Author and oversee documentation through all stages in GCLP-regulated clinical sample testing.

• PhD in Biology or Chemistry related sciences and at least 5 or more years of industrial experience applying translational biomarker technologies for discovery and/or clinical research.
• Extensive experience in assay development, GCLP validation, and implementation of soluble biomarker assays for clinical studies.
• Extensive experience and thorough understanding of immunochemical techniques, protein biochemistry, LC-MS, molecular biology techniques.
• Excellent organizational skills and familiarity with a fast-paced work environment.

• Experience with assay development for MSD, Quanterix, ELISA, NuLISA, LC-MS, qPCR platforms/techniques

Arrowhead provides competitive salaries and an excellent benefit package.

Candidates must have current, valid authorization to work in the country where this role is located.