Associate Scientist, Molecule

Associate Scientist, Large Molecule (LM)

Location:

Malvern, Pennsylvania, United States of America. Job Function:
Discovery & Pre-Clinical/Clinical Development. Job Sub Function:
Biotherapeutics R&D. Job Category:
Scientific/Technology.

• Support biologics drug product development activities from discovery through commercialization, collaborating with global Chemistry and Manufacturing Controls (CMC) teams at Johnson & Johnson’s Innovative Medicine.
• Use physical, chemical, and biological principles to identify mechanisms and kinetics governing process and product performance, and scale up to achieve target process performance at all scales.
• Develop fundamental understanding of large molecule parenteral process unit operations (freeze/thaw, mixing, filtration, filling) and conduct Process Analytical Technology (PAT)‑based experiments.
• Create and use lab‑based “scale‑down” models to evaluate process parameters and ranges, building knowledge for scale‑up of unit operations.
• Evaluate the suitability of manufacturing processes to existing product, process, and material platforms.
• Collaborate with development, commercial, and clinical supply chain teams to conduct in‑depth reviews of process performance data, establish or refine process improvements.
• Develop process engineering skills, including use of multi‑physics software for process modeling and statistical analysis of data.
• Participate in development activities that meet all regulatory requirements and expectations for large molecule fill‑finish manufacturing processes.
• Travel up to 15% internationally and domestically.

• Bachelor’s degree in Engineering (Biomedical, Bioengineering, Chemical, Electrical, or Mechanical) with 0‑3 years experience (including co‑ops, internships, or research), OR Master’s degree with ~0‑1 year of work experience.
• Basic understanding of manufacturing principles and processes, preferably applied to large molecule production.
• Ability to perform data evaluation and statistical analysis.
• Ability to write technical documents and clearly communicate findings and progress to management.
• Experience collaborating in matrix teams to deliver high‑quality results.
• Motivated, self‑starter, able to work independently with proven problem‑solving skills.

• Analytical Reasoning, Biochemistry, Chemistry, Manufacturing & Control (CMC), Clinical Trial Protocols, Collaboration, Data Quality, Drug Discovery Development, Execution Focus, Molecular Diagnostics, Pharmacogenetics, Problem Solving, Research Documents, Scientific Research, Technologically Savvy, Troubleshooting, Written Expression.

Johnson & Johnson is an Equal Opportunity Employer. All qualified applicants will receive consideration for employment without regard to race, color, religion, sex, sexual orientation, gender identity, age, national origin, disability, protected veteran status or any other characteristic protected by federal, state or local law. Johnson & Johnson actively seeks qualified candidates who are protected veterans and individuals with disabilities as defined under VEVRAA and Section 503 of the Rehabilitation Act.

Johnson & Johnson is committed to providing an interview process that is inclusive of applicants’ needs.