Clinical Fellow

Overview

We seek an ambitious, innovative individual with a specific interest in early phase clinical trials to act as sub‑investigator for a growing portfolio of complex clinical trials. The role offers an exciting opportunity to work with a highly motivated & empowered team to deliver innovative research. With Consultant oversight, you will be responsible for seeing new referrals, follow‑ups & managing the patient throughout all aspects of their trial experience.

ECMT leads a regular molecular tumour board meeting supporting both local and national studies. You will take an active role in these meetings gaining valuable experience in using these data to identify and define suitable trial options for patients. This is a 10 session non‑training post. The position is suitable for individuals who have or expect to complete IMT by August 2026, through to those having completed their specialist training in Oncology, and who wish to gain further experience in experimental medicine and Phase I trials, including first‑in‑human trials, clinical pharmacology trials and translational research.

The post holder will work as part of the Experimental Cancer Medicine Team, providing medical support to the consultants by primarily acting as sub‑investigator on a large portfolio of clinical trials. The post holder will be responsible for seeing new referrals, follow‑ups and for managing the patient throughout all aspects of their trial experience. ECMT has a well‑established and regular molecular tumour board meeting supporting both local and national studies.

The post holder will take an active role in these meetings gaining valuable experience in using these data to identify and define suitable trial options for patients. The post holder will have the opportunity to be involved in audit, writing papers and reviews and there is the potential to present research work at local, national, or international meetings. The post holder will join a highly motivated and empowered workforce to increase research capacity and deliver innovative early phase research in compliance with Good Clinical Practice (ICH‑GCP) and Trust policy.

This is a 10 session non‑training post (salary scale dependent on experience) funded through The Christie NHS Foundation Trust for an initial period of 1 year.

• See new referrals and manage patient throughout all aspects of the trial experience.
• Follow‑up patients and coordinate all aspects of trial care.
• Attend safety review committee meetings (usually remotely) to discuss trial patients.
• Interface with external stakeholders such as CROs and pharmaceutical sponsors.
• Attend monthly molecular tumour board meetings to discuss trial patients and agree opportunities for patients to enroll in early phase trials.
• Attend 4–5 trial outpatient clinics per week (see indicative timetable).

• Manage all aspects of trial patients in outpatient and in‑patient settings, including new patient consultation, consent, screening and follow‑up appointments.
• Participate in phase I trials of small molecule inhibitors, next‑generation chemotherapy trials, combination/multi‑modality Phase I trials, molecular characterisation/translational studies, and radiotherapy trials.
• Attend safety review committee meetings and molecular tumour board meetings to discuss trial patients.
• Assist in the development and planning of new studies.

• Maintain a level of continuing professional development consistent with the recommendations of the Royal College of Physicians.
• Potential to present research work and write papers and reviews.
• Annual appraisal required.

The closing date for this post may be extended if there are insufficient applicants or brought forward if there is a high volume of applicants. If you have not heard from us within four weeks of the closing date, I regret that on this occasion your application will have been unsuccessful. Sponsorship information:
The Christie is an approved sponsoring organisation. Applications will be considered from applicants requiring sponsorship alongside all other applications. Please be aware that not all roles are eligible for…