University assistant predoctoral

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At the University of Vienna almost 11,000 personalities work together towards answering the big questions of the future. Around 7,700 of them do research and teaching, around 3,000 work in administration and organisation. We are looking for a/an

50 Faculty of Life Sciences

Job :
5255

Detailed description

Are you interested in cellular mechanisms of neurotoxicity and how pathologically altered proteins damage different cell types in the central nervous system? Would you like to conduct research on neurodegeneration, neuroinflammation, and vascular involvement in the brain in an experimental environment?

Then we look forward to welcoming you as a Praedoc University Assistant at the University of Vienna. The advertised PhD project is translational in nature and deals with the cellular toxicity of pathologically modified α-synuclein species in relevant in vitro models of the central nervous system.

As a Praedoc university assistant, you will join Associate Prof. Marietta Zille, PhD's research team in the field of cellular and molecular neuro- and vascular pharmacology. You will be involved in a clearly structured PhD project and work independently on scientific questions.

The research focus of the working group is on regulated cell death mechanisms, the neurovascular unit and blood-brain barrier, stroke and cerebral hemorrhage, neuroinflammation, cellular senescence, and innovative in vitro models for investigating neurodegenerative processes.

Associate Prof. Zille's team currently consists of a postdoc, predocs, and administrative colleagues and has a strong international network. What sets us apart as a team is a clear scientific profile, methodological excellence, a high degree of personal responsibility, a collegial working atmosphere, and the targeted promotion of young scientists. Scientific integrity, critical thinking, and teamwork are particularly important to us.

You actively participate in research, teaching & administration, which means:

• You will work on an experimental PhD project in the field of neurodegeneration, cellular neurotoxicity, and glial stress responses
• You will plan and conduct in vitro experiments with primary cells of the central nervous system, especially neurons and glial cells
• You will investigate the effects of toxic stimuli on cell viability, cell death, and cellular stress and inflammatory responses
• You will apply established cell biological, molecular biological, and microscopic methods and evaluate them quantitatively
• You will work with models of the blood-brain barrier to analyze barrier function and transport processes
• We expect the dissertation agreement to be completed within 12-18 months
• You will work continuously on your dissertation and its timely completion
• You will hold courses in accordance with the provisions of the collective agreement
• You will take on administrative tasks in research and teaching

• Completed master's or diploma degree in pharmacy, biology, biomedicine, molecular biology, neuroscience, or a related field, or about to complete a relevant degree
• Proven practical experience working with primary cell cultures, ideally from the central nervous system
• Experience with experimental models of cellular damage or cell death induction
• Familiarity with quantitative cell viability or cell death assays is an advantage
• Experience in independently planning and conducting laboratory experiments
• Interest in neurodegenerative or cerebrovascular diseases, neuroinflammation, or cellular stress mechanisms
• Very good written and spoken English skills (C1 level)
• Careful, structured way of working and strong team and communication skills
• Interest in university teaching and further scientific qualification

Experience with glial cells, neurovascular issues, or models of acute cellular damage is a particular advantage.

Employment: The position is advertised…