Lipid Nanoparticle & mRNA Synthesis Intern - Marlborough, MA

* Onsite role based at our Marlborough, MA site*

• Conduct systematic experiments of in vitro transcription (IVT) reaction on benchtop bioreactors; collect and analyze the data.

• Develop and execute protocols for preparing and characterizing nucleic acid–loaded lipid nanoparticle (LNP) formulations using automated LNP synthesis platforms.

• Support LNP process development activities, including screening, scale-up, and manufacturing-relevant workflow optimization.

• Troubleshoot issues with experimental design and execution.

• Collect, analyze, and interpret experimental data; prepare technical summaries and present results in internal meetings and reviews.

• Current graduate student in biomedical, chemical, mechanical engineering, or related field with formal education and experience with lipid nanoparticles and/or nucleic acids.

• Hands‑on laboratory experience with RNA synthesis, preferably including in vitro transcription.

• Experience with LNP formulation and characterization, including techniques such as dynamic light scattering (DLS), nanoparticle tracking analysis (NTA), Ribo Green assay, HPLC, chromatography, capillary electrophoresis, ELISA, or related assays.
  
  Ideal to have an experience with one or more of the following: dynamic light scattering (DLS), nanoparticle tracking analysis, Ribo Green assay, HPLC, chromatography, capillary electrophoresis, ELISA

• Familiarity with microfluidic instruments, laboratory automation, 3D printing, advanced cell models, or conjugation reactions is a plus.

• Strong oral and written communication skills, with the ability to summarize results and present findings clearly.

• Identification with our core values:
  Sustainability, Openness, Enjoyment

Compensation is up to $30 an hour. No relocation and/or accommodations are offered.

• Personal and Professional Development:
  Mentoring, leadership programs, internal seminar offerings
• Making an Impact Right from the Start:
  Comprehensive onboarding, including a virtual online platform
• Welcoming Culture:
  Mutual support, team spirit and international collaboration; communities on numerous topics such as “Coaching”, “Agile Working” and a “Businesswomen’s Network”
• Intelligent Working Environment:
  Working in smart buildings with the latest technology and equipment.

Sartorius is an equal opportunity employer and will consider all qualified applicants for employment without regard to race, color, religion, sex, national origin, age, protected veteran status, disability or based on status in any other protected group of class.

Please view equal employment opportunity posters provided by OFCCP here.

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Sartorius is part of the solution in the fight against cancer, dementia, and many other diseases. Our technologies help translate scientific discoveries into real-world medicine faster, so that new therapeutics can reach patients worldwide. We look for ambitious team players and creative minds, who want to contribute to this goal and advance their careers in a dynamic global environment. Join our global team and become part of the solution.

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