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Senior Metabolic & Biomanufacturing Process Engineer Security Clearance

Job in Laurel, Howard County, Maryland, 20723, USA
Listing for: Johns Hopkins University Applied Physics Laboratory
Full Time position
Listed on 2026-06-29
Job specializations:
  • Engineering
    Research Scientist
Job Description & How to Apply Below
Position: Senior Metabolic & Biomanufacturing Process Engineer with Security Clearance
Location: Laurel

Description Do you marvel at the complexity of metabolism and seek to leverage natural metabolisms in creative ways to develop new technologies? Do you want to apply your expertise in biomanufacturing process engineering to pressing National Security challenges? Do you love contributing your microbial metabolic engineering and downstream processing subject matter expertise to an interdisciplinary team of scientists, focused on developing novel applications?

If you answered yes to these questions, we're looking for someone like you to join our team in the Biological Sciences Group, here at the Johns Hopkins University Applied Physics Lab. We are seeking a highly motivated metabolic and bioprocess engineer to contribute to a team focused on engineering microbial metabolic pathways and optimizing biomanufacturing processes, including upstream and downstream processing.

As part of the Biological Sciences Group, in the Research Exploratory Development Department, you will be at the forefront of APL's mission to provide impactful contributions to critical challenges. You will contribute to building outstanding expertise in molecular biology, in the pursuit of challenges in national security. As a Senior Metabolic & Biomanufacturing Process Engineer...
* Design, implement, and characterize recombinant metabolic pathways in microbial organisms.
* Design, implement, and optimize biomanufacturing processes.
* Lead projects and teams for both internally funded and externally funded efforts in the research areas mentioned above.
* Support new business development activities to expand program scope within the Research and Exploratory Development Department and other business areas across APL, including concept development, proposal writing, and project execution.
* Work with a technical team providing leadership in the development of new opportunities and support internal initiatives, driving technical innovation and growth in areas relevant to APL sponsors.
* Participate in the broader APL community by presenting data to interdisciplinary groups and to department management.

* Develop and maintain effective working relationships with external sponsors. Qualifications You meet our minimum qualifications for the job if you...
* Have a PhD in Biological Engineering, Chemical Engineering, Molecular Biology or a similar field.

* Have extensive wet lab experience manipulating the metabolism of microbes and in scaling metabolite synthesis and downstream processing.
* Have 2+ years experience with analytical chemistry techniques and equipment including: HPLC, GC/MS, or LC/MS.

* Are proficient in molecular biology techniques, including DNA manipulation and plasmid construction, qPCR, protein analysis, plate-reader assay development, microscopy techniques, and microbial cell culture.
* Have experience designing, executing, and troubleshooting a wide range of biological assays.
* Possess strong leadership skills, including excellent written and verbal communication skills, demonstrated through a combination of publication record, teaching, and professional experience.
* Are able to obtain an Interim Secret level security clearance by your start date and can ultimately obtain a TS/SCI level clearance. If selected, you will be subject to a government security clearance investigation and must meet the requirements for access to classified information. Eligibility requirements include U.S. citizenship.
You'll go above and beyond our minimum requirements if you...
* Have experience working with non-lab adapted or anaerobic microbes, including such as Rhodopseudomonas palustris and Pseudomonas aeruginosa.
* Have experience with yeast, plant, algae, or microbiome systems. About Us Why Work at APL? The Johns Hopkins University Applied Physics Laboratory (APL) brings world-class expertise to our nation's most critical defense, security, space and science challenges. While we are dedicated to solving complex challenges and pioneering new technologies, what makes us truly outstanding is our culture. We offer a vibrant, welcoming atmosphere where you can bring your authentic self to work, continue to grow, and build strong…
Position Requirements
10+ Years work experience
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