Scientist, Downstream Process Development

Location: Devens

Working with Us

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You'll get the chance to grow and thrive through opportunities uncommon in scale and scope, alongside high-achieving teams. Take your career farther than you thought possible.

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Position Summary:

The Scientist position will be part of the Biologics Downstream Development department in Devens, MA that is responsible for early and late stage process development of BMS' growing biologics pipeline. The candidate will be responsible for developing efficient, robust, and scalable downstream purification processes - including chromatography and filtration unit operations - for therapeutic biologics. The candidate will be working in a dynamic and collaborative team environment with opportunities to lead development and matrix teams, while enhancing our ever-growing biologics portfolio.

Key Responsibilities:

* Develop and implement scalable purification processes for biologics drugs to meet established timelines.

* Design, execute and perform data analysis for downstream process development laboratory studies, including protein A affinity, ion exchange, hydrophobic interaction, and mixed-mode chromatography, as well as ultrafiltration/diafiltration (UF/DF), membrane filtration and depth filtration processes.

* Organize and interpret results, present to matrix team and management.

* Support process scale-up and tech transfer activities in pilot plant and clinical manufacturing sites.

* Support clinical manufacturing by reviewing documents and/or using technical expertise to ensure successful manufacturing campaigns.

* Author electronic notebook records, process descriptions, process development reports, and other documentation/technical reports for progression of assets and/or support of regulatory filings.

Qualifications &

Experience:

* PhD in Biotechnology, Protein Chemistry, Biochemistry or Chemical/Biochemical Engineering, with 0-2 years, or MS with 2-4 years, or BS with 5-7 years of relevant industrial and/or academic experience preferred.

* Hands-on experience with downstream bioprocessing unit operations, including chromatography (e.g., affinity, ion exchange, HIC) OR membrane-based separations (e.g., UF/DF, depth filtration), is required.

* Knowledge of protein purification, protein stability, and demonstrated experimental skills for laboratory work are required.

* Knowledge of protein characterization and analytical techniques is preferred.

* Knowledge of statistical experimental design and data analysis is preferred.

* Critical qualities include a high degree of initiative, good verbal and written communication skills, strong scientific skills and attention to detail, and the ability to work collaboratively in a team environment.

If you come across a role that intrigues you but doesn't perfectly line up with your resume, we encourage you to apply anyway. You could be one step away from work that will transform your life and career.

Compensation Overview:

Devens - MA - US: $103,080 - $124,908

The starting compensation range(s) for this role are listed above for a full-time employee (FTE) basis. Additional incentive cash and stock opportunities (based on eligibility) may be available. The starting pay rate takes into account characteristics of the job, such as required skills, where the job is performed, the employee's work schedule, job-related knowledge, and experience. Final, individual compensation will be decided based on demonstrated experience.

Eligibility for specific benefits listed on our careers site may vary…