Staff Scientist

Staff Scientist

We are currently searching for a Staff Scientist to provide laboratory leadership and support services to perform interdisciplinary and collaborative research from bench to beside with the National Heart, Lung, and Blood Institute (NHLBI). This is a full-time, on-site opportunity in Bethesda, MD.

Responsibilities include:

• Combine biochemical, molecular, cellular, genetic, and quantitative approaches to investigate fundamental biological processes across a range of organisms.
• Research how cells sense, respond, and adapt to a variety of stress conditions.
• Address how alterations in mTOR, TFEB, TFE3, and lysosomal function lead to human disease.
• Seek to identify potential sites for therapeutic intervention suitable for further evaluation in translational and clinical research efforts.
• Serve as laboratory lead contributing to training and mentoring of all laboratory members.
• Present research at meetings and conferences.
• Work in an interdisciplinary lab collaborating with others to advance research initiatives.
• Characterize the contribution of lysosomes to a variety of physiological processes, both in normal and pathological conditions.

Qualifications include:

• PhD with MINIMUM TWO (2) years of postdoctoral research experience in molecular biology, cellular biology, biochemistry, or related field.
• Mastery of Zebrafish models with skills such as husbandry, genetic crossing, and genotyping protocols.
• Strong publication record.
• Experience working with animal models.
• Expertise in cellular biology and advanced microscopy imaging.
• Ability to obtain and maintain a Federal or DoD Public Trust.

Nice to have:

• Knowledge of organelle cell biology (lysosomes, autophagy, intracellular trafficking), and a commitment to conducting related high-quality research.
• Ability to work independently and in a team setting.
• Excellent oral and written communication abilities.
• Outstanding interpersonal and time management skills.
• Demonstrated experience in staff training and mentoring.

Guidehouse offers a comprehensive, total rewards package that includes competitive compensation and a flexible benefits package that reflects our commitment to creating a diverse and supportive workplace.