Associate Scientist - Epigenetic of Pediatric Brain Disease - Jamy Peng Lab

The Associate Scientist performs a variety of moderately complex research tasks determined by the field and scope of the particular research project or study. Also, performs tasks related to the research project independently, but within broad guidelines and subject to periodic review by a supervisor or other research staff. The lab of Jamy Peng in the Department of Developmental Neurobiology e Children’s Research Hospital is seeking an Associate Scientist to investigate how genomic DNA organization and gene regulation within stem cells influence their function and identity, explore chromatin structure, histone modifications and their impact on gene expression in stem cells, and contribute to uncovering the molecular basis of pediatric cancer and normal development.

• Strong background in developmental biology, molecular biology, stem cell biology, or closely related fields.
• Deep understanding of epigenetics, including chromatin structure and organization, histone modifications, epigenetic regulation of gene expression, and protein–RNA interactions in stem cells.
• Hands‑on experience with techniques commonly used to interrogate epigenetic mechanisms (e.g., ChIP‑seq, ATAC‑seq, RNA‑seq, CRISPR‑based perturbation, imaging assays, stem cell assays).
• Strong competence in designing, executing, and troubleshooting independent experiments using existing or newly developed protocols.

• Independently perform experiments using existing, modified, or newly developed techniques and protocols.
• Set up protocols using new or modified laboratory techniques and troubleshoot experiments independently.
• Identify experimental data pertinent to the analysis problem; process, organize, and summarize data; report results.
• Assist in the drafting and editing of manuscripts, posters, SOPs, and policies.
• Maintain up‑to‑date knowledge of the field and related techniques.
• Provide ongoing support for monitoring, maintenance, ordering, and purchasing of equipment and supplies as needed.
• Perform calibration of instruments and equipment as necessary.
• Provide guidance and training to less‑experienced team members and may also train others outside the lab in relevant techniques.
• Perform other duties as assigned to meet the goals and objectives of the department and the institution.
• Maintain regular and predictable attendance.

Bachelor’s degree in a relevant scientific area.

• 7+ years of research experience is required.
• 5+ years of research experience is required with a Master’s degree.
• 2+ years of research experience is required with a PHD.

• Experience leading and supporting research experiments.
• Some experience leading lab and scientific project coordination, maintenance, and other research support activities.
• Experience in guiding and training other laboratory personnel.
• Proven performance in earlier role/comparable role.

Compensation range: $65,520 – $114,400 per year for the role of Associate Scientist – Epigenetic Basis of Pediatric Brain Disease – Jamy Peng Lab.

Please direct your questions and application package, including a cover letter, current CV, and 3 letters of reference to: jamy.peng.

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Jude.