Postdoctoral Research Associate - Pharmacy and Pharmaceutical Sciences

Postdoctoral Position Overview

A postdoctoral position is available in the laboratory of Samuel W. Brady. The lab focuses on identifying and therapeutically targeting key dependencies in pediatric solid tumors (Banu et al., Science Advances 12:eaeb
3503 (2026) http://(Use the "Apply for this Job" box below)..aeb
3503 and cancer genomics, including mutational signatures (Brady et al., Cancer Discovery 2026 ). This position involves the experimental study of key pediatric cancer dependencies, and the identification of new approaches to target them therapeutically. It includes studies of protein signaling, subcellular relocalization, pharmacological studies using existing small molecule inhibitors, and the study of newly-developed compounds and approaches to inhibit essential childhood cancer dependencies.

With a general background in cancer biology, pharmacology, and/or chemical biology, the ideal candidate would be familiar with cancer models, protein analysis (such as Western blot and immunoprecipitation), microscopy, cell culture, and molecular biology techniques. This position may also involve the experimental study of mutational signatures in pediatric cancer. We are seeking an ambitious, proactive, and creative postdoctoral fellow with a strong interest in basic and translational cancer research.

Applicants should have a recent PhD degree. This position is experimental and will involve interfacing with computational genomics colleagues in the lab.

• Perform experimental studies of key pediatric cancer dependencies.
• Identify new therapeutic approaches to target these dependencies.
• Conduct research on protein signaling and subcellular relocalization.
• Carry out pharmacological studies with existing small‑molecule inhibitors and new compounds.
• Study mutational signatures in pediatric cancer.
• Collaborate with computational genomics colleagues.

• Recent PhD degree in cancer biology, pharmacology, chemical biology, or related field.
• Experience with cancer models and protein analysis techniques (Western blot, immunoprecipitation).
• Proficiency in microscopy, cell culture, and molecular biology methods.
• Ambitious, proactive, and creative, with a strong interest in basic and translational cancer research.
• Capacity to work independently and in a collaborative research environment.

To apply, please submit a brief cover letter describing your research interests, goals, and how these align with the research in the laboratory, your CV, and contact information for three references.

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