Postdoctoral Research Associate - Wu Lab

Postdoctoral Research Fellow – Cancer Metabolism and Immunometabolism

We are seeking motivated postdoctoral fellows with a track record of productivity and strong interest in cancer metabolism and immunometabolism. Applicants should have a recent doctoral degree (PhD, MD, or combined degrees), with a general background in molecular and cell biology, biochemistry, and genetics.

A Postdoctoral Research Fellow position is available to study molecular regulation of nucleotide metabolism across diverse human pathophysiological contexts. Our laboratory aims to uncover fundamental mechanisms governing metabolic reprogramming and translate these discoveries into therapeutic strategies for human disease (Wu et al., Cell Metabolism, 2024, PMID: ; Wu et al., Science, 2025, PMID: ). We employ multidisciplinary approaches, including CRISPR-based functional genomics, stable isotope tracing, metabolomics, molecular and cellular biology, biochemistry, and mouse models to investigate how nucleotide metabolism influences disease progression and treatment response.

• Study molecular regulation of nucleotide metabolism across diverse human pathophysiological contexts.
• Employ multidisciplinary approaches such as CRISPR-based functional genomics, stable isotope tracing, metabolomics, molecular and cellular biology, biochemistry, and mouse models.
• Investigate how nucleotide metabolism influences disease progression and treatment response.

• Recent doctoral degree (PhD, MD, or combined degrees).
• Strong background in molecular and cell biology, biochemistry, and genetics.
• Track record of productivity in relevant research areas.
• Strong interest in cancer metabolism and immunometabolism.

Our laboratory is committed to creating a supportive, inclusive, and collaborative environment. Postdoctoral fellows will receive individualized mentorship, opportunities to develop independent research programs, and strong support for career advancement in academia.

St. Jude Children’s Research Hospital, Memphis, Tennessee.

To apply please include a cover letter, CV and the names and contact information of three references.

St. Jude is an Equal Opportunity Employer.

St. Jude Children's Research Hospital does not accept unsolicited assistance from search firms for employment opportunities. Please do not call or email. All resumes submitted by search firms to any employee or other representative e via email, the internet or in any form and/or method without a valid written search agreement in place and approved by HR will result in no fee being paid in the event the candidate is hired by St.

Jude.