Scientist, Elitzur Lab

Job Description Summary The World's Brightest Minds Always Innovate e Children's Research Hospital, we know what can be achieved when the brightest scientific minds face the fewest barriers. That is why we provide world-class facilities. State-of-the-art technologies. Extraordinary support. And a collaborative, bench-to-bedside environment where you can see, firsthand, how your science translates into survival for the children we serve. Quite simply, e, we encourage you to dream big and stop at nothing when it comes to finding cures and saving children.

The laboratory of Dr. Sarah Elitzur in the Department of Oncology, St. Jude Children's Research Hospital, is seeking a research scientist to lead investigations into rare and understudied subgroups of hematologic malignancies. Our lab is focused on characterizing the genomic, molecular, and clinical features of uncommon hematologic malignancy subtypes, with the goal of defining novel biological mechanisms and identifying therapeutic vulnerabilities for patient populations that remain underrepresented in mainstream research.

This is an excellent opportunity for a scientist interested in working at the intersection of rare disease biology, precision medicine, and translational hematology-oncology. The successful candidate will perform and coordinate a wide range of laboratory research procedures and conduct complex research projects within the field of pediatric leukemia and lymphoma. This role requires the ability to perform a variety of advanced laboratory techniques independently, analyze and interpret experimental data, and present research findings.

The individual will contribute to ongoing research initiatives while supporting the development of new experimental approaches and technologies that advance the laboratory's scientific goals.

• Coordinates multiple aspects of research projects and carries out laboratory experiments utilizing various laboratory techniques, and determines whether additional or other tools or methods are required
• Provides input regarding research protocols and experiments
• Sets up protocols and assists in developing new laboratory techniques as required
• Identifies experimental data pertinent to the analysis problem
• Processes, organizes and summarizes data, reporting these experimental results as required
• Monitors quality and integrity of recorded information and data
• May draft sections of research manuscripts
• Provides basic lab operation support to include equipment maintenance and purchasing
• Monitors inventory levels and orders lab supplies as needed
• Performs calibration of instruments and equipment
• Troubleshoots instrument performance and equipment issues
• Lead and manage research projects focused on the molecular characterization of hematologic malignancies
• Design and execute experiments using genomic, transcriptomic, and functional approaches to define disease mechanisms
• Integrate and analyze large-scale sequencing and clinical datasets, including collaboration with international consortia when relevant
• Establish and maintain patient-derived models representing rare disease subtypes
• Contribute to manuscript preparation, grant writing, and presentation of findings at scientific conferences
• Maintain meticulous records and ensure regulatory compliance for human subjects research
• Instructs other staff in basic laboratory techniques and procedures
• Maintains regular and predictable attendance
• Performs other related duties as assigned in order to meet the goals of the department and institution

• Ph.D. and/or equivalent research experience in cancer biology, genetics, genomics, molecular biology, or a related field
• Demonstrated experience with genomic and/or transcriptomic analysis (e.g., RNA-seq, WES/WGS, single-cell sequencing)
• Experience working with rare disease cohorts, biobanked samples, or multi-institutional data sharing is a strong plus
• Strong analytical and bioinformatics skills, or willingness to collaborate closely with computational biologists
• Track record of scientific productivity (publications, presentations) appropriate to career stage
• Excellent organizational and communication skills, with the ability to manage multiple concurrent projects
• Experience mentoring trainees is desirable

• Bachelor's degree in relevant scientific area is required

• Eight (8) years of relevant work experience is required
• Six (6) years of relevant work experience is required with a Master's degree
• Three (3) years of relevant work experience is required with a PhD

In recognition of certain U.S. state and municipal pay transparency laws, St. Jude is including a reasonable estimate of the compensation range for this role. This is an estimate offered in good faith and a specific salary offer takes into account factors that are considered in making compensation decisions including but not limited to skill sets, experience and training, licensure and certifications, and other…