Postdoctoral Research Associate
Listed on 2026-08-09
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Research/Development
Immunology Research, Research Scientist, Clinical Research, Postdoctoral Research Fellow
Postdoctoral Position
St. Jude Children's Research Hospital, Memphis, Tennessee, USA
We are seeking a highly motivated and ambitious postdoctoral fellow to join the group of Dr. Giedre Krenciute. The lab is located in the Department of Bone Marrow Transplantation and Cellular Therapy e Children's Research Hospital in Memphis, TN. Our lab is working on highly translational immunology research, with the focus on brain tumors. We use genetically engineered human or murine T cells to design novel, long-lasting and safe therapeutic approaches for pediatric brain tumors.
Major projects include:
- Designing, generating, and optimizing chimeric antigen receptors (CARs) specific for pediatric brain tumors.
- Enhancing CAR T cell effector function and longevity using different genetic manipulations
- Studying brain tumor microenvironment and its effect on CAR T cell function
In addition to a Ph.D., the candidate should have expertise in the following techniques (all highly preferred but not required):
- Molecular biology techniques (DNA related work (propagation in bacteria, isolation, PCR), RNA related work (isolation, qPCR), WB, CRISPR)
- Cloning (ligation cloning, any iteration of Gibson Assembly (InFusion, NEBuilder, etc)) and plasmid design using Snap Gene (or equivalent software)
- Tissue culture (tumor and immune cells)
- Flow cytometry
- Transfection, transduction, and transformation.
- Immunology methods (cytokine detection by ELISAs and/or flow, immune cell isolation from animals, etc)
- Animal work
Training in brain tumor biology, immunology and/or CAR T cell biology is highly advantageous but not necessary.
Fluency in English is essential. Candidates should have the ability to work independently as well as in a collaborative research team and have a strong desire to make a major contribution to the field of CAR T cell biology. The fellow will benefit from the outstanding research facilities and the highly collaborative St. Jude community. In addition, the fellow will interact and work with the leaders in basic and translational immunology and brain tumor biology research within and outside the institution.
Interested applicants should send their CV, a cover letter describing research experience and interests, and names and email addresses of three references to: giedre.krenciute
St. Jude Children's Research Hospital is an equal opportunity employer.
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