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Senior​/Principal Software Engineer, Rust Genomics Infrastructure

Job in Memphis, Shelby County, Tennessee, 37544, USA
Listing for: St. Jude Children's Research Hospital
Full Time position
Listed on 2026-06-17
Job specializations:
  • Software Development
    Software Engineer, Senior Developer, AI Engineer (Applied/Software), Software Architect
Salary/Wage Range or Industry Benchmark: 80000 - 100000 USD Yearly USD 80000.00 100000.00 YEAR
Job Description & How to Apply Below
Position: Senior Staff / Principal Software Engineer, Rust Genomics Infrastructure

Senior Staff / Principal Software Engineer, Rust Genomics Infrastructure

Location:

Memphis, TN

Category:
Computational Sciences

Department:
Computational Biology

Shift: Weekday Day

Position Type:
Full Time

Scheduled Weekly

Hours:

40

Job Description

The Senior Staff Software Engineer manages assigned software systems through strategic direction, technical design, implementation, and operational health. The Principal Software Engineer anticipates, identifies, and provides solutions for complex problems through deep technical analysis. St. Jude is seeking a seasoned Rust developer to lead the development of software to facilitate genomics analysis  position will focus on writing or rewriting tools that underpin the genomics ecosystem in Rust.

A deep understanding of Rust programming language, algorithm optimization, and strong documentation and testing practices are required. A portion of the time will be dedicated to open‑source software development, requiring active community management and engagement. Both synchronous and asynchronous communication skills are essential for project direction, progress tracking, and community engagement. Specific experience with bioinformatics and genomics is not required;

we target talented software engineers who want to expand into these fields.

Senior Staff Software Engineer – Responsibilities
  • Independently manage software systems within an area of responsibility, providing strategic direction, technical design, implementation, and operational health, coordinating efforts with other staff as necessary.
  • Serve as a technology advocate and technical thought leader within the assigned area, inspiring productive change through technology solutions, guiding application strategy, and providing recommendations for future development.
  • Architect, design, and develop best‑in‑class solutions to all but the most complex problems in the scientific domain.
  • Use scientific domain knowledge to perform data analysis and identify problems and areas for improvement and generate strategic leads.
  • Stay educated on existing and state‑of‑the‑art technologies, evaluate technology fits for effective delivery.
  • Engage with and influence senior leadership and other decision‑makers.
  • Participate in preparation of scientific manuscripts and presentations.
  • Drive processes for continuous learning and development across teams, mentoring and guiding when required to ensure quality and productivity.
  • Perform other duties as assigned to meet the goals and objectives of the department and institution.
  • Maintain regular and predictable attendance.
Senior Staff Software Engineer

Minimum Education and/or Training
  • Bachelor's degree in computer science, data science, information science, business, or related field.
  • Master's degree preferred.
Senior Staff Software Engineer – Minimum Experience
  • Minimum Requirement:
    Bachelor's degree with 8+ years of experience in computer science, data science, information science, business, or related field.
  • Experience Exception:
    Master's degree with 6+ years of experience in the same fields.
  • Experience with programming languages, databases, and software development lifecycle.
  • Substantial experience within the technical and/or scientific domain.
  • Proven performance in earlier role or comparable role.
Principal Software Engineer – Responsibilities
  • Anticipate problems and opportunities in the scientific domain; advocate for strategic plans based on deep technical and scientific knowledge.
  • Independently perform deep analysis of scientific data to identify problems and opportunities for improvement.
  • Mentor junior staff in technical and scientific concepts and actively contribute to the local body of knowledge.
  • As part of a multi‑disciplinary team, identify technical solutions to complex scientific problems and lead the implementation of those solutions.
  • Serve as a technology advocate and technical thought leader within the assigned area, inspiring productive change through technology solutions, guiding application strategy, and providing recommendations for future development.
  • Prepare scientific manuscripts and presentations.
  • Perform other duties as assigned to meet the goals and objectives of the department…
Position Requirements
10+ Years work experience
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