Senior Software Developer

St. Jude Children's Research Hospital is seeking a Senior Software Developer to join our team. This position reports to the Director of High Performance Research Computing and works closely with the Center for Bioimage Informatics as a collaborative team member.

The Center for Bioimage Informatics is a dynamic, close-knit, and focused team dedicated to supporting the life-changing research conducted e by developing and applying innovative AI and computer vision approaches for image analysis and quantification. We are looking for an individual motivated to make a meaningful impact through software development focused on image generation, management, analysis, and processing.

The ideal candidate will have proven experience in full-stack, open-source web development, with strong proficiency in Java, Python, and JavaScript, as well as modern application frameworks such as Node.js and Spring. Experience with RESTful API design and integration, including familiarity with Model Context Protocol (MCP) or similar tool‑calling frameworks, is expected. Experience with relational database technologies is required, with PostgreSQL experience strongly preferred.

Given the bioimaging focus of this work, experience with image formats, OME Bio-Formats, microscopy techniques, imaging systems, and AI/ML-driven software development is a plus. Additional technologies in use include Docker, Maven, Git, Zarr, and Dask.

Candidates should demonstrate experience designing and developing object‑oriented software solutions. This is a hands‑on development role in which the successful candidate will spend a significant portion of their time architecting, building, integrating, and testing software as part of robust, production‑ready solutions.

The Senior Software Developer is responsible for developing software to support object‑oriented software applications.

This is an onsite role in Memphis, TN.

• Leads software coding, testing, debugging, documenting, and installation, and may be responsible for one or more of these components, as directed.
• Leads the design of the system’s graphical user interface.
• Assists in developing detailed specifications for programs to be written for enterprise-wide systems.
• Develops the detailed specifications from which programs will be written for group-level systems.

• Perform the detailed design, coding and testing of software utilizing established design/code standards and to the architectural patterns outlined by the architectural team.
• Design and implement new systems and features, as well as modify and maintain existing systems for adaptation to business and/or technology changes.
• Manage projects and provide subject matter expertise for production systems, document maintenance and system support procedures.
• Support continuous improvement by investigating alternatives and new technologies and presenting these for architectural review.
• Determine root cause for the most complex software issues and develop practical, efficient, and permanent technical solutions.
• Collaborate with internal teams and vendors to fix and improve products.
• Remain current on new technologies and available vendor packages; evaluate and make recommendations as necessary.
• Train and mentor junior teams on emerging technology systems and applications related aspects.
• Perform other duties as assigned to meet the goals and objectives of the department and institution.
• Maintains regular and predictable attendance.

• Bachelor's degree in computer science, data science, information science, business, or related field required.

• Minimum experience:
  
  4+ years of IT experience in systems programming and development, preferably in comparable industry.
• Experience in SDLC methodologies (e.g. Agile, Waterfall, CI/CD).
• Experience in software systems design and maintenance.
• Experience working with business stakeholders to identify and document requirements.
• Proven performance in earlier role/comparable role.

• Proven experience in full-stack, open-source web development with strong proficiency in Java, Python, and JavaScript.
• Experience with…