Associate Director​/Director, Accounting & Technical Accounting

More than one million people in the United States today are fighting blood cancer. While a traditional allogeneic stem cell transplant has been the best hope for many, the transplant itself can prove fatal or lead to serious conditions, such as graft vs. host disease. Orca Bio is a late-stage biotechnology company redefining the transplant process by developing next‑generation cell therapies with the goal of providing significantly better survival rates with dramatically fewer risks.

With our purified, high‑precision investigational cell therapies we hope to not only replace patients' blood and immune systems with healthy ones, but also restore their lives.

This role plays a critical leadership role within the controllership function at Orca Bio. It will oversee key accounting and reporting activities, including financial reporting, general ledger accounting, internal controls, and technical accounting matters.

The ideal candidate thrives in a fast‑paced, high‑growth biotech environment and brings a hands‑on, “roll‑up‑your‑sleeves” mindset. This role requires strong technical expertise, sound judgment, and the ability to identify and resolve issues proactively while effectively communicating with cross‑functional stakeholders. A deep commitment to Orca Bio’s mission and values is essential.

• Partner with the Controller to support the financial close process, including review of journal entries and account reconciliations.
• Lead trial balance reviews, analyze variances, and ensure timely resolution of discrepancies.
• Support and coordinate the annual external audit process and related audit requests.
• Maintain and enhance the chart of accounts and ensure systems and controls support the integrity of financial data and processes.
• Lead clinical trial accounting activities, including developing and maintaining study‑level accounting models, accrual methodologies, and cost tracking processes to ensure accurate and timely recognition of clinical research expenses.
• Assist in annual testing of process‑ and company‑level internal controls, as assigned.
• Ensure general ledger accounting complies with U.S. GAAP and provide guidance on emerging technical accounting issues and new accounting standards.
• Oversee equity (stock) administration in coordination with the Company’s third‑party service provider, including ensuring accuracy of stock transactions, proper accounting treatment, and alignment with financial reporting requirements.
• Manage investor reporting in accordance with reporting obligations, ensuring accuracy, timeliness, and consistency with internal financial reporting and external requirements.
• Collaborate closely with the accounting team to maintain best‑in‑class performance and continuous improvement.
• Partner effectively with cross‑functional teams and executive leadership to support operational and strategic initiatives.

• Bachelor’s degree in accounting, Business, Economics, or a related field required; CPA license strongly preferred.
• 10+ years of accounting experience with 5+ years managing financial reporting at a publicly traded or private company. Biotech or life science industry experience is strongly preferred.
• A proven leader with strong technical capabilities with deep expertise in GAAP and SEC reporting; demonstrated experience in the preparation of relevant SEC/external filings.
• Experience managing accounting close process and performing related analyses.
• Proven experience developing sound financial analyses, explanations and recommendations.
• Excellent written and verbal communication skills and experience developing and making presentations to C‑level executives.
• Proven self‑starter with experience improving finance functions; ability to work well in a team environment and across organizational disciplines.
• Understanding SOX/404 compliance requirements.

The anticipated annual salary range for this job is based on prior experience in the role/industry, education, location, internal equity, and other job‑related factors as permitted by law. For remote‑based positions,…