Scientist I​/II

About Diagnose Early

Diagnose Early is making non-invasive breath testing a mainstream technology. Our mission right now is to use toxin testing and fitness monitoring to help our users detect health risks early. Our long-term vision is to use the data we collect to diagnose health conditions early.

To achieve this, we have assembled a truly world-class team that brings together technical expertise, academic excellence, medical knowledge, and business acumen. The team is working to achieve the best outcomes for all our users and to deliver our mission and vision.

For more Information, visit

Position Details

Position Title:

Scientist I/II

Department: R & D group

FLSA Status:
Exempt

Location:

Menlo Park, CA

Salary Range: $120,000 - $160,000 per annum

Reports to:

Chief Science Officer

Scope of Job

Job Summary:

This Scientist I/II position will drive research and carry out experiments in support of efforts to measure compounds in breath and other biological materials. This is a hands-on position that offers opportunities for innovation of experimental techniques. The position is to be based in our San Francisco Bay Area R&D laboratory.

Essential Functions

To include, but are not limited to the following:

• Develop, optimize and validate analytical methods primarily using Thermo Scientific Q-Exactive and Exploris mass spectrometers using LC-MS and other types of mass spectrometric methods to identify and quantify metabolic compounds and exogenous compounds (including carcinogens and toxins).
• Create laboratory developed tests (LDTs) to be implemented in a CLIA environment.
• Design, implement bench-scale experiments with multiple variables for small molecule compounds.
• Be a champion for data quality making judgment calls on qualitative and quantitative validity of analytical data and drive the directions of research projects towards definite conclusions.
• Collaborate cross-functionally with other R&D teams and successfully communicate with people who have little or no knowledge of mass spectrometry and metabolomics.
• Maintain meticulous experimental records.
• Mentor junior team members.
• Voice ideas, concerns, and solutions as an active team member.
• Being able to work in an environment which comes with shifting priorities.

QUALIFICATIONS GUIDELINES

To include, but are not limited to the following:

• Ph.D. degree in Analytical Chemistry, Chemistry, Biochemistry or related fields.
• For Scientist II, 3+ years of postdoctoral hands-on laboratory (academic and/or industrial) experience developing analytical methods for small molecule analysis (LC, MS, GC). For Scientist I, 0-3 years postdoctoral experience.
• Ability to be a fully independent user of LC-MS and knowledge of instrumentation hardware and software.
• Proficiency in Solid Phase Extraction (SPE) is a plus.
• Experience using the Thermo Scientific Q-exactive platform is essential, including data analysis using both Thermo software and open-source software.
• Proficiency in untargeted and targeted metabolomics and lipidomics data processing, statistical analysis and data interpretation is essential.
• Proficiency using Python based analysis tools is desirable.
• Strong problem-solving skills and proven creativity.
• Strong oral and written communication skills.
• Demonstrated ability to work effectively within a diverse and dynamic team.
• Start-up company experience is a plus.

Physical Requirements:

standing, sitting, walking, stairs, light lifting, computer operation.

Diagnose Early is an equal opportunity employer. Diagnose Early offers a competitive compensation package including medical/dental, 401K, paid time off, holidays, and equity.