Senior Analytical Scientist

Senior Analytical Scientist

Location:

Menlo Park, CA
Pay Rate: $85,

Advance Peptide Discovery with Cutting-Edge Mass Spectrometry

Staffmark is seeking an experienced Senior Analytical Scientist for a consulting opportunity supporting an innovative peptide discovery program. If you have hands‑on expertise with Thermo Orbitrap mass spectrometers, nanoLC-MS/MS method development, and peptide sequence identification, this is an excellent opportunity to work on high‑impact research with potential for recurring project assignments.

• M.S. or Ph.D. in Analytical Chemistry, Biochemistry, Mass Spectrometry, or a related scientific field
• Equivalent industry experience will be considered

• 3+ years of hands‑on experience with nano-flow LC-MS/MS on Thermo instrumentation
• Experience operating and troubleshooting Thermo Orbitrap mass spectrometers and Xcalibur software
• Strong knowledge of peptide MS/MS fragmentation and database‑based sequence identification
• Experience developing and optimizing nanoLC-MS workflows

• Perform high‑sensitivity nano‑flow LC-MS/MS analysis of peptide samples
• Develop and optimize nanoLC-MS/MS methods and MS/MS acquisition parameters
• Configure and operate a Thermo Orbitrap XL and Thermo Dionex Ulti Mate 3000 NanoLC system
• Analyze and interpret LC-MS/MS data for peptide sequence identification
• Perform instrument maintenance, calibration, troubleshooting, and performance optimization
• Resolve nanoLC system issues involving flow paths, columns, emitters, and electrospray stability
• Document analytical methods, results, and recommendations
• Collaborate with scientific teams to support peptide hit identification

• Ability to work in a laboratory environment and operate precision analytical instrumentation
• Strong attention to detail and ability to manage multiple project priorities

• Medical, dental, vision, and pet insurance
• 401(k) Retirement Savings Plan
• Employee Assistance Program (EAP)
• Commuter/Parking Accounts
• People Perks
• Health Savings Account (HSA)
• AD&D Insurance

Perform advanced peptide analysis, optimize nanoLC-MS/MS methods, troubleshoot high‑performance instrumentation, interpret complex mass spectrometry data, and contribute to breakthrough discovery research.